Resolution of left atrial appendage thrombus with apixaban

Thrombosis Journal

Hiroki Ishihara¹  Nobukiyo Tanaka¹  Hiroyoshi Ohno¹  Hiroko Kobayakawa¹  Tohru Kawakami¹ 

[1] From the Division of Cardiology, Ichinomiyanishi Hospital, 1 Kaimei-hira, Ichinomiya, Aichi, Japan

关键词: Apixaban;    Left atrial appendage thrombus;    Atrial fibrillation;   

Others  :  834778
DOI  :  10.1186/1477-9560-11-26

 received in 2013-09-05, accepted in 2013-11-17,  发布年份 2013

【 摘 要 】

Left atrial appendage (LAA) thrombosis is an important cause of cardiogenic cerebral thromboembolism. Apixaban is a member of the class of novel oral anticoagulants (NOAC) and is superior to warfarin in preventing stroke or systemic embolism, causes less bleeding, and results in lower mortality in patients with atrial fibrillation. There are few reports of resolution of LAA thrombus with other NOAC. We present a 72-year-old male patient with persistent atrial fibrillation associated with left atrial thrombus. Sixteen days of apixaban treatment showed complete thrombus resolution. In this study, soluble fibrin and D-dimer levels decreased without prolongation of international normalized ratio (INR) and activated partial thromboplastin time (APTT).

【 授权许可】

   
2013 Kawakami et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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