Wound healing after radiation therapy: Review of the literature

Radiation Oncology

Holger G Gassner¹  Jürgen Strutz¹  Fabian Pohl²  Elisabeth Ohmann¹  Frank Haubner¹ 

[1] Department of Otorhinolaryngology, Division of Facial Plastic Surgery, University of Regensburg, Regensburg, Germany;Department of Radiotherapy, University of Regensburg, Regensburg, Germany

关键词: Radiation therapy;    Wound healing;   

Others  :  1155262
DOI  :  10.1186/1748-717X-7-162

 received in 2012-06-18, accepted in 2012-09-20,  发布年份 2012

【 摘 要 】

Radiation therapy is an established modality in the treatment of head and neck cancer patients. Compromised wound healing in irradiated tissues is a common and challenging clinical problem. The pathophysiology and underlying cellular mechanisms including the complex interaction of cytokines and growth factors are still not understood completely. In this review, the current state of research regarding the pathomechanisms of compromised wound healing in irradiated tissues is presented. Current and possible future treatment strategies are critically reviewed.

【 授权许可】

   
2012 Haubner et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

Fig. 2.

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