Prevalence and risk factors of Strongyloides stercoralis in Takeo Province, Cambodia

Particle and Fibre Toxicology

Peter Odermatt³  Sinuon Muth¹  Meng Chuor Char¹  Philipp J Bless³  Hanspeter Marti²  Fabian Schär³  Virak Khieu³ 

[1] National Centre for Parasitology, Entomology and Malaria Control, Ministry of Health, Phnom Penh, Cambodia;Medical and Diagnostics Department, Swiss Tropical and Public Health Institute, Basel, Switzerland;University of Basel, Basel, Switzerland

关键词: Cambodia;    Clinical manifestation;    Risk factors;    Prevalence;    Strongyloides stercoralis;   

Others  :  806742
DOI  :  10.1186/1756-3305-7-221

 received in 2013-11-24, accepted in 2014-04-28,  发布年份 2014

【 摘 要 】

Background

The threadworm Strongyloides stercoralis, the most neglected helminth, affects an estimated 30-100 million people worldwide. Information on S. stercoralis infection is scarce in tropical and sub-tropical resource poor countries, including Cambodia. We determined S. stercoralis infection prevalence and risk factors for infection in the general population in Southern Cambodia.

Methods

A cross-sectional study was carried out between January and April 2011 among 2,861 participants living in 60 villages of Takeo province, using Koga-agar plate culture, the Baermann technique and the Kato-Katz technique on a single stool sample.

Results

Eight intestinal helminth species were diagnosed. Hookworm (31.4%) and S. stercoralis (21.0%) occurred most frequently. Prevalence of S. stercoralis infection increased with age. In all age groups a higher prevalence was found among males than among females (OR: 1.7; 95% CI: 1.4 – 2.0; P < 0.001). Participants who had a latrine at home were significantly less frequently infected with S. stercoralis than those who did not (OR: 0.7; 95% CI: 0.4 – 0.8; P = 0.003). Muscle pain (OR: 1.3; 95% CI: 1.0 – 1.6; P = 0.028) and urticaria (OR: 1.4; 95% CI: 1.1 – 1.8; P = 0.001) were significantly associated with S. stercoralis infection.

Conclusions

S. stercoralis is highly prevalent among the general Cambodian population and should no longer be neglected. Access to adequate diagnosis and treatment is urgently needed.

【 授权许可】

   
2014 Khieu et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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