1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara | |
A comparison of the immune response between early exposed and 1 year post exposure to Bacillus anthracis in Indonesia | |
Redhono, D.^1 ; Kusumawardani, A.^2 ; Dirgahayu, P.^3 | |
Sub Division of Tropical Medicine and Infectious Disease, Faculty of Medicine, Sebelas Maret University, Moewardi Hospital, Surakarta, Indonesia^1 | |
Departement of Dermatology Venerology, Faculty of Medicine, Sebelas Maret University, Moewardi Hospital, Surakarta, Indonesia^2 | |
Departement of Biomedicine, Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia^3 | |
关键词: Bacillus anthracis; Clinical manifestation; Direct contact; Exposed to; Immune response; Post-exposure; Risk factors; Zoonotic disease; | |
Others : https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012012/pdf DOI : 10.1088/1755-1315/125/1/012012 |
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来源: IOP | |
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【 摘 要 】
Anthrax is one of the zoonotic diseases that usually affects animals and can be transmitted to humans. Immune response of the body during an infection is the presence of antibodies as an effort to defend the body and it will survive for some time in the blood. The aim study is to find out how the initial response to the formation of antibodies and how these antibodies survive after one year. This study is cohort to people exposed to anthrax and found 130 people exposed to anthrax. The most risk factor was direct contact and consumed infected animal meat, which was 34.6%. Clinical manifestations of the skin were 12.3% and all respondents showed positive IgG. While 87.7% did not show any anthrax symptoms. IgG serum examination after 1 year of exposure to anthrax obtained 3.8% still detected antibodies in the body. The relationship between IgG titers with clinical manifestations of anthrax at one year post-outbreak is highly significant p 0.028. In conclusion a significant association between the clinical manifestation with antibody serum anthrax and it still detected after one-year post outbreaks of anthrax.
【 预 览 】
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A comparison of the immune response between early exposed and 1 year post exposure to Bacillus anthracis in Indonesia | 352KB | ![]() |