Effects of kiwi consumption on plasma lipids, fibrinogen and insulin resistance in the context of a normal diet

Nutrition Journal

Luis Garcia-Ortiz⁵  Cristina Agudo-Conde⁵  Angela de Cabo Laso⁵  Jose A. Maderuelo-Fernandez⁵  Luis Otegui-Ilarduya⁴  Aventina de la Cal de la Fuente¹  Nere Mendizabal-Gallastegui³  Blanca Notario-Pacheco²  Elisa Puigdomenech⁷  Maria C. Patino-Alonso⁸  Manuel A. Gomez-Marcos⁵  Jose I. Recio-Rodriguez⁶ 

[1] Casa del Barco Health Center, Castilla and León Health Service–SACYL, Valladolid, Spain;Cuenca III Health Centre, Castilla La Mancha Health Service–SESCAM, Cuenca, Spain;Primary Care Research Unit of Bizkaia, Basque Health Care Service-Osakidetza, Bilbao, Spain;Torre Ramona Health Center, Aragón Health Service–Salud, Zaragoza, Spain;La Alamedilla Health Centre, Castilla and León Health Service–SACYL, redIAPP, IBSAL, Salamanca, Spain;Unidad de Investigación, Centro de Salud La Alamedilla, Avda. Comuneros 27-31, Salamanca, 37003, Spain;Passeig de Sant Joan Health Center, Catalan Health Center, Barcelona, Spain;Statistics Department, University of Salamanca, Salamanca, Spain

关键词: Insulin resistance;    HDL;    Cholesterol;    Fibrinogen;    Actinidia;   

Others  :  1226177
DOI  :  10.1186/s12937-015-0086-0

 received in 2015-05-27, accepted in 2015-09-10,  发布年份 2015

【 摘 要 】

Background and aims

Among fruits, kiwi is one of the richest in vitamins and polyphenols and has strong anti-oxidant effects. We aimed to analyze the relationship between the consumption of kiwi and plasma lipid values, fibrinogen, and insulin resistance in adults within the context of a normal diet and physical-activity.

Methods

Cross-sectional study. Participants (N = 1469), who were free of cardiovascular diseases, completed a visit, which included the collection of information concerning the participant’s usual diet and kiwi consumption using a previously validated, semi-quantitative, 137-item food-frequency-questionnaire. Fasting laboratory determinations included plasma lipids, fibrinogen and insulin resistance. Regular physical-activity was determined using accelerometry.

Results

Consumers of at least 1 kiwi/week presented higher plasma values of HDL-cholesterol (mean difference 4.50 [95 % CI: 2.63 to 6.36]) and lower triglyceride values (mean difference −20.03 [95 % CI: −6.77 to −33.29]), fibrinogen values (mean difference −13.22 [95 % CI: −2.18 to −24.26]) and HOMAir values (mean difference −0.30 [95 % CI: −0.09 to −0.50]) (p < 0.05, for all comparisons) than those who consumed less than 1 kiwi per week. In an adjusted logistic regression analysis, this group had a lower odds-ratio for presenting plasmatic fibrinogen concentrations above 400 mg/dL (OR = 0.68, 95 % CI 0.49 to 0.95), HDL-Cholesterol plasma values below 45 mg/dL (OR = 0.57, 95 % CI 0.36 to 0.91) and a HOMAir above 3 (OR = 0.61, 95 % CI 0.37 to 1.00).

Conclusions

Consumption of at least one kiwi/week is associated with lower plasma concentrations of fibrinogen and improved plasma lipid profile in the context of a normal diet and regular exercise.

【 授权许可】

   
2015 Recio-Rodriguez et al.

【 图 表 】

Fig. 1.

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