Bacteriophages as antimicrobial agents against major pathogens in swine: a review

Journal of Animal Science and Biotechnology

Yongping Xu³  Shuying Li⁴  Xiaoyu Li²  Lili Wang²  Zhenhui Cao¹  Zhen Li²  Jiancheng Zhang³ 

[1] Faculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China;School of Life Science and Biotechnology, Dalian University of Technology, Dalian 116024, China;Ministry of Education Center for Food Safety of Animal Origin, Dalian 116600, China;Dalian SEM Bio-Engineering Technology Co. Ltd., Dalian 116620, China

关键词: Swine;    Phage therapy;    Food safety;    Bacteriophage;    Antibiotic resistance;   

Others  :  1224548
DOI  :  10.1186/s40104-015-0039-7

 received in 2014-12-08, accepted in 2015-08-04,  发布年份 2015

【 摘 要 】

In recent years, the development of antibiotic resistant bacteria has become a global concern which has prompted research into the development of alternative disease control strategies for the swine industry. Bacteriophages (viruses that infect bacteria) offer the prospect of a sustainable alternative approach against bacterial pathogens with the flexibility of being applied therapeutically or for biological control purposes. This paper reviews the use of phages as an antimicrobial strategy for controlling critical pathogens including Salmonella and Escherichia coli with an emphasis on the application of phages for improving performance and nutrient digestibility in swine operations as well as in controlling zoonotic human diseases by reducing the bacterial load spread from pork products to humans through the meat.

【 授权许可】

   
2015 Zhang et al.

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