Genome sequencing, annotation and analysis of Salmonella enterica sub species salamae strain DMA-1

Gut Pathogens

Javed N Agrewala¹  Shanmugam Mayilraj²  Nida Mubin¹  Sheenam Verma¹  Amit Arora²  Gurwinder Kaur²  Sathyaseelan Sathyabama¹ 

[1] Immunology Laboratory, CSIR-Institute of Microbial Technology, Sector 39-A, Chandigarh, India;Microbial Type Culture Collection and Gene bank (MTCC), CSIR-Institute of Microbial Technology, Sector 39-A, Chandigarh, India

关键词: EzTaxon;    RAST;    Salmonella enterica subspecies salamae;   

Others  :  817542
DOI  :  10.1186/1757-4749-6-8

 received in 2014-03-07, accepted in 2014-04-03,  发布年份 2014

【 摘 要 】

Background

The genus Salmonella is Gram-negative which belongs to the family Enterobacteriaceae. In this study, we have sequenced the whole genome of the strain DMA-1, which was isolated from mouse stool sample and identified as Salmonella enterica subspecies salamae.

Results

The strain DMA-1 was closely related at the 16S rRNA gene sequence level with the members of the genus Salmonella: Salmonella enterica subspecies salamae DSM 9220^T (100%), followed by Salmonella enterica subspecies diarizonae (99.1%), Salmonella enterica subspecies enterica (99.0%) and Salmonella enterica subspecies indica (98.5%). We obtained the draft genome of S. enterica subspecies salamae strain DMA-1 with a size of 4,826,209 bp and mean G+C content of 52.0 mol%.

Conclusions

We for the first time, sequenced the entire genome of the strain DMA-1 which was isolated from the mouse stool sample and identified it as Salmonella enterica, sub species salamae. Further, we subjected the whole genome sequencing data for annotation that revealed several genes responsible for the pathogenesis, virulence, defense, metabolism and other genomic features.

【 授权许可】

   
2014 Sathyabama et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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