Reliability and validity of a single item measure of quality of life scale for adult patients with cystic fibrosis

Health and Quality of Life Outcomes

Kevin Webb²  Julie Morris³  Mary Dodd²  Abebaw M Yohannes¹ 

[1] Department of Health Professions, Research Institute for Health and Social Change, Manchester Metropolitan University, Elizabeth Gaskell Campus, Hathersage Road, M13 0JA, UK;Department of Adult Cystic Fibrosis Unit, University of South Manchester, Wythenshawe Hospital, Manchester, Southmoor Road, M23 9LT, UK;Department of Medical Statistics, 1st Floor, Education & Research Centre, University Hospital of South Manchester, Wythenshawe Hospital, Southmoor Road, Manchester, M23 9LT, UK

关键词: CF-QOL;    HRQOL;    adult;    concurrent validity;    reliability;    cystic fibrosis;    single-item global scale;    Quality of life;   

Others  :  826232
DOI  :  10.1186/1477-7525-9-105

 received in 2011-04-28, accepted in 2011-11-25,  发布年份 2011

【 摘 要 】

Background

It is important to monitor health related quality of life in order to determine the efficacy of interventions and physical functioning of patients with cystic fibrosis in their daily activities. There is no a single-item global quality of life scale for routine clinical practice for adult patients with cystic fibrosis. We assessed the reliability and validity of a single-item global quality of life scale and compared with the Cystic Fibrosis Quality of Life Questionnaire (CF-QOL) for adult patients with cystic fibrosis.

Method

121 (men = 66, women = 55) adult cystic fibrosis patients self-completed the CF-QOL, the Hospital Anxiety Depression Scale, and the single item global quality of life scale at the out patient clinic. 33 (17 women) completed the repeat questionnaires at home within two weeks. Socio-demographic characteristic and lung function data were extracted from the recent medical notes.

Results

Mean (SD) age was 29.6 (8.9) years and mean (SD) forced expiratory volume in 1 second was 2.20 (0.94) litres. The test-retest reproducibility using the intra-class correlation coefficient (ICC) for the CF-QOL was 0.83, 95% confidence interval 0.68 to 0.91. The single item global quality of life ICC score was 0.78, 95% confidence interval 0.59 to 0.88. Concurrent validity of the single-item global quality of life was examined in relation to all items of the CF-QOL, frequent episodes of readmission, anxiety and depression (all, p < 0.01) were moderately correlated.

Conclusion

The study provides preliminary evidence that the single-item quality of life scale is acceptable, valid and repeatable for adult patients with cystic fibrosis. It is a promising tool that can be easily incorporated into a routine clinical practice to assess patients' quality of life.

【 授权许可】

   
2011 Yohannes et al; licensee BioMed Central Ltd.

【 图 表 】

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