Maternal and fetal outcome of pregnancy related hypertension in Mettu Karl Referral Hospital, Ethiopia

Journal of Ovarian Research

Netsanet Fentahun²  Million Tesfaye³  Mubarek Abera⁴  Eshetu Seyom¹ 

[1] Department of Obstetrics/Gynecology and Surgery Coordinating Office, Jimma University, Jimma, Ethiopia;Department of Health Education and Behavioral Sciences, Jimma University, Jimma, Ethiopia;Department of Anesthesia, Jimma University, Jimma, Ethiopia;Department of Psychiatry, Jimma University, Jimma, Ethiopia

关键词: Low resource country;    Eclampsia;    Preeclampsia;    Hypertension;    Gestational;   

Others  :  1145467
DOI  :  10.1186/s13048-015-0135-5

 received in 2014-11-06, accepted in 2015-02-19,  发布年份 2015

【 摘 要 】

Background

Hypertensive disorders of pregnancy are the most common causes of adverse maternal & perinatal outcomes. Such investigations in resource limited settings would help to have great design strategies in preventing maternal and perinatal morbidity and mortality.

Aim

To determine management outcome and factor associated with pregnancy related hypertensive disorder in Mettu Karl Referral Hospital, Mettu, Ethiopia.

Method

A retrospective study deign was conducted at Mettu Karl Referral Hospital from 1^st January 2010 to December 1^st 2013 by reviewing medical records and logbooks. Descriptive, binary and multiple logistic regression analysis were used. A 95% CI and P- value of < 0.05 were considered statistically significant.

Result

The magnitude of pregnancy related hypertensive disorder was 2.4%. Majority 82.6% of the mothers were in the age range between 18 to 34 year with a mean age and standard deviation (SD) of 24.4 (SD ± 5.12). Sever preeclampsia was the most prevalent diagnosis made to 35.5% of the mother, followed by 19% cases of eclampsia and 12.4% of HELLP. Fetal management outcomes indicates 120.37 perinatal mortality per 1000 deliveries and a stillbirth rate of 10.2%, low birth weight of 30.5%, and low APGAR score of 18.5%, abortion 10.7% and preterm delivery 31.4%.

Conclusion

In this study severe preeclampsia is the most common of all pregnancy related hypertension disorders followed by Eclampsia. Fetal complications like low Apgar score and preterm deliveries were statistically significant and associated with fetal management outcomes.

【 授权许可】

   
2015 Seyom et al.; licensee BioMed Central.

【 图 表 】

Figure 1.

Figure 2.

【 参考文献 】

• [1]Report of the national high blood pressure education program working group on high blood pressure in pregnancy. Am J Obstet Gynecol. 2000; 183(1):s1-22.
• [2]Brown MA, Hague WM, Higgins J, Lowe S, McCowan L, Oats J et al.. The detection, investigation and management of hypertension in pregnancy: executive summary. Aust N Z J Obstet Gynaecol. 2000; 40(2):133-8.
• [3]Sibai BM. Diagnosis and management of gestational hypertension and preeclampsia. Obstet Gynecol. 2003; 102(1):181-92.
• [4]Sibai B, Dekker G, Kupferminc M. Pre-eclampsia. Lancet. 2005; 365(9461):785-99.
• [5]Reingardiene D. Preeclampsia and eclampsia. Medicina (Kaunas). 2003; 39(12):1244-52.
• [6]Tubbergen P, Lachmeijer AM, Althuisius SM, Vlak ME, Van Geijn HP, Dekker GA. Change in paternity: a risk factor for preeclampsia in multiparous women? J Reprod Immunol. 1999; 45(1):81-8.
• [7]Young BC, Levine RJ, Karumanchi SA. Pathogenesis of preeclampsia. Annu Rev Pathol. 2010; 5:173-92.
• [8]Singhal SR, Deepika A, Nanda S. Maternal and perinatal outcome in severe pre-eclampsia and eclampsia. J South Asian Federation of Obstetrics Gynecol. 2009; 1(3):25-8.
• [9]Walker JJ. Pre-eclampsia. Lancet. 2000; 356(9237):1260-5.
• [10]Backes CH, Markham K, Moorehead P, Cordero L, Nankervis CA, Giannone PJ. Maternal preeclampsia and neonatal outcomes. J Pregnancy. 2011; 2011:214365.
• [11]Osungbade KO, Ige OK: Public health perspectives of preeclampsia in developing countries: implication for health system strengthening. J Pregnancy 2011., 481095.
• [12]Yucesoy G, Ozkan S, Bodur H, Tan T, Caliskan E, Vural B et al.. Maternal and perinatal outcome in pregnancies complicated with hypertensive disorder of pregnancy: a seven year experience of a tertiary care center. Arch Gynecol Obstet. 2005; 273(1):43-9.
• [13]Gaio DS, Schmidt MI, Duncan BB, Nucci LB, Matos MC, Branchtein L. Hypertensive disorders in pregnancy: frequency and associated factors in a cohort of Brazilian women. Hypertens Pregnancy. 2001; 20(3):269-81.
• [14]Dolea C, AbouZahr C. [http://www.who.int/evidence/bod] webcite Global burden of hypertensive disorders of pregnancy in the year 2000. GBD 2000 Working Paper, World Health Organization: Geneva. . 2003b.“Global Burden of Obstructed Labor in the Year 2000.” GBD 2000 Working Paper, World Health Organization, Geneva. http://www.who.int/evidence/bod webcite, 2003
• [15]Abalos E, Cuesta C, Carroli G, Qureshi Z, Widmer M, Vogel JP et al.. Pre-eclampsia, eclampsia and adverse maternal and perinatal outcomes: a secondary analysis of the World Health Organization Multicountry Survey on Maternal and Newborn Health. BJOG. 2014; 121:14-24.
• [16]Caritis S, Sibai B, Hauth J, Lindheimer M, VanDorsten P, Klebanoff M et al.. Predictors of pre-eclampsia in women at high risk. Am J Obstet Gynecol. 1998; 179(4):946-51.
• [17]Misra DP, Kiely JL. The association between nulliparity and gestational hypertension. J Clin Epidemiol. 1997; 50(7):851-5.
• [18]Sibai BM. Management of preeclampsia. Clin Perinatol. 1991; 18(4):793-808.
• [19]Hall DR, Odendaal HJ, Steyn DW, Grové D. Expectant management of early onset, severe pre-eclampsia: maternal outcome. BJOG. 2000; 107(10):1252-7.
• [20]Aali BS, Ghafoorian J, Mohamad-Alizadeh S. Severe preeclampsia and eclampsia in Kerman, Iran: complications and outcomes. Med Sci Monit. 2004; 10(4):CR163-7.
• [21]Gilbert WM, Nesbitt TS, Danielsen B. The cost of prematurity: quantification by gestational age and birth weight. Obstet Gynecol. 2003; 102(3):488-92.
• [22]Onwujekwe O, Uzochukwu B. Socio-economic and geographic differentials in costs and payment strategies for primary healthcare services in Southeast Nigeria. Health Policy. 2005; 71(3):383-97.
• [23]Aggarwal R, Mishra V, Jasani A, Gumber M. Acute renal failure in pregnancy: Our experience. Saudi J Kidney Dis Transpl. 2014; 25(2):450.
• [24]Ansari MR, Laghari MS, Solangi KB. Acute renal failure in pregnancy: one year observational study at Liaquat University Hospital, Hyderabad. JPMA J Pak Med Assoc. 2008; 58(2):61.