Early gastric cancer with suspected brain metastasis arising eight years after curative resection: a case report

BMC Research Notes

Kosei Hirakawa¹  Masaichi Ohira¹  Kiyoshi Maeda¹  Masakazu Yashiro¹  Hiroaki Tanaka¹  Naoshi Kubo¹  Ryosuke Amano¹  Takahiro Toyokawa¹  Akihiro Murata¹  Kazuya Muguruma¹  Katsunobu Sakurai¹ 

[1] Department of Surgical Oncology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka City, Osaka 545-8585, Japan

关键词: Whole-brain radiation therapy;    Brain metastasis;    Gastric cancer;   

Others  :  1123212
DOI  :  10.1186/1756-0500-7-818

 received in 2014-05-29, accepted in 2014-11-03,  发布年份 2014

【 摘 要 】

Background

Brain metastasis from gastric cancer is fairly uncommon and prognosis is dismal. We report a case of early gastric cancer with brain metastasis arising 8 years after gastrectomy.

Case presentation

A 78-year-old Japanese female presented to our hospital complaining of dizziness, 8 years after undergoing gastrectomy for gastric cancer. Histopathological type of the tumor was well-differentiated adenocarcinoma. Final TNM classification was T1b(sm1)N0M0, and pathological stage was IA. Further examination revealed a metastatic tumor in the cerebellum and multiple liver metastases. The brain metastasis was treated using radiotherapy and steroid. Systemic treatment for liver metastases was performed using the oral fluoropyrimidine drug S-1. Neurological symptoms decreased, enabling the patient to be discharged from hospital. However, chemotherapy was discontinued due to loss of appetite and general fatigue. She died 5 months after the diagnosis of brain metastasis due to progressive disease.

Conclusions

Cases of brain metastasis arising 8 years after gastrectomy for early gastric cancer have rarely reported. Aggressive treatment for brain metastases may be effective for improvement of the damage to neurological function and quality of life.

【 授权许可】

   
2014 Sakurai et al.; licensee BioMed Central Ltd.

【 图 表 】

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