Men’s knowledge and attitudes towards dietary prevention of a prostate cancer diagnosis: a qualitative study

BMC Cancer

J Athene Lane⁴  David E Neal¹  Freddie C Hamdy²  Jenny L Donovan³  Chris Metcalfe³  Kerry NL Avery³  Jeremy P Horwood³ 

[1]Department of Oncology, University of Cambridge, Addenbrooke’s Hospital, Cambridge CB2 0QQ, UK

[2]Nuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK

[3]School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK

[4]National Institute for Health Research Bristol Nutrition Biomedical Research Unit, University Hospitals Bristol NHS Foundation Trust, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK

关键词: Qualitative research;    Prostatic neoplasms;    Lycopene;    Green Tea;    Diet;   

Others  :  1120233
DOI  :  10.1186/1471-2407-14-812

 received in 2014-02-20, accepted in 2014-10-24,  发布年份 2014

【 摘 要 】

Background

Prostate cancer (PC) incidence and progression may be influenced by dietary factors, but little is known about the acceptability of dietary modification to men at increased risk of PC. Qualitative interviews with men participating in the ProDiet study were undertaken to explore the feasibility of implementing dietary interventions for the prevention of prostate cancer.

Methods

An interview study nested within the ProDiet randomised feasibility trial of dietary interventions to prevent a PC diagnosis. Men (n = 133) who previously participated in community based prostate specific antigen (PSA) testing without PC but who were at increased risk of the disease were randomly allocation to both lycopene (lycopene or placebo capsules or lycopene rich diet) and green tea (green tea or placebo capsules or green tea drink) for 6 months. Semi-structured interviews were conducted with participants shortly after randomisation, to investigate attitudes towards dietary modification for PC prevention and dietary information. Interviews were audio-recorded, transcribed and analysed to identify common themes.

Results

Interviews were conducted with 21 participants aged 52-72 years with PSA levels between 2.5 and 2.95 ng/ml, or a negative prostate biopsy result. Most men identified the major causes of cancer in general to include diet, environment, ageing and genetic factors. This contrasted sharply with men’s uncertainty about PC aetiology, and the function of the prostate. Men were confused by conflicting messages in the media about dietary practices to promote health overall, but were positive about the potential of lycopene and green tea in relation to PC prevention, valuing their natural components. Furthermore these men wanted tailored dietary advice for PC prevention from their clinicians, whom they considered a trusted source of information.

Conclusion

Men at elevated risk of PC reported uncertainty about PC aetiology and the role of diet in PC prevention, but enthusiasm for dietary modifications that were perceived as ‘simple’ and ‘natural’. The men looked to clinicians to provide consistent disease specific dietary advice. These factors should be taken into consideration by clinicians discussing elevated PSA results with patients and those planning to embark on future trials investigating dietary modification interventions for the prevention of a PC diagnosis.

【 授权许可】

   
2014 Horwood et al.; licensee BioMed Central Ltd.

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