BMC Research Notes | |
Effective palliative radiofrequency ablation for tumors causing pain, numbness and motor function disorders: case series | |
Yukio Miki1  Masao Hamuro2  Akira Yamamoto1  Tomohisa Okuma1  Toshiyuki Matsuoka1  Shinichi Hamamoto1  | |
[1] Department of Radiology, Graduate School of medicine, Osaka City University, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan;Depertment of Radiology, Osaka Saiseikai Nakatsu Hospital, 2-10-39 Sibata, Kita-ku, Osaka 530-0012, Japan | |
关键词: Carcinomatous neuropathy; Palliative treatment; Radiofrequency ablation; | |
Others : 1125796 DOI : 10.1186/1756-0500-7-765 |
|
received in 2013-11-08, accepted in 2014-10-13, 发布年份 2014 | |
【 摘 要 】
Background
We present a case series of a palliative radiofrequency ablation (RFA) for the tumors that lead to the resolution of pain and motor function disorders. RFA is widely used on tumors in various organs and often reported in good outcome. There are some reports that RFA was performed as a palliative treatment but a few reports of RFA that performed for lung tumor as a palliative treatment. This case series includes two cases, palliative RFA for a sacrum and a lung tumor. The results of this case series presented that a palliative RFA is effective in improving the symptoms of patients.
Case presentation
Case 1. A 64-year-old Japanese woman with a chordoma at her sacrum presented with pain in her left leg and claudication. Though operations, radiation therapy and GS-TAE (gelatin sponge–transarterial embolization, via the L5 lumbar artery) were performed, the size of the tumor leading pain and claudication increased. RFA was performed for the sacral tumor, and these symptoms resolved one year after the procedure.
Case 2. A 68-year-old Japanese man with a leiomyosarcoma at the apex of left lung presented with pain and motor function disorders of the left upper limb. Dissemination in the pleura was appeared after the operation for a leiomyosarcoma at the mediastinum. Though radiation therapy and a second operation were performed, the tumor at the apex of the left lung increased and pain and numbness of the left upper limb were appeared after the second operation. RFA was performed for the left lung tumor, and the symptoms resolved 3 months after RFA.
Conclusion
RFA is effective as a palliative treatment and has a potential to salvage the patients from the symptoms of the tumors when conventional palliative treatments such as surgery, radiation therapy, and chemotherapy are difficult or contraindicated.
【 授权许可】
2014 Hamamoto et al.; licensee BioMed Central Ltd.
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
20150217025337230.pdf | 879KB | download | |
Figure 6. | 65KB | Image | download |
Figure 5. | 43KB | Image | download |
Figure 4. | 66KB | Image | download |
Figure 3. | 67KB | Image | download |
Figure 2. | 80KB | Image | download |
Figure 1. | 61KB | Image | download |
【 图 表 】
Figure 1.
Figure 2.
Figure 3.
Figure 4.
Figure 5.
Figure 6.
【 参考文献 】
- [1]Ahmed M, Brace CL, Lee FT Jr, Goldberg SN: Principles of and advances in percutaneous ablation. Radiology 2011, 258(2):351-369.
- [2]Okuma T, Matsuoka T, Yamamoto A, Oyama Y, Toyoshima M, Nakamura K, Inoue Y: Frequency and risk factors of various complications after computed tomography-guided radiofrequency ablation of lung tumors. Cardiovasc Intervent Radiol 2008, 31(1):122-130.
- [3]Gazelle GS, Goldberg SN, Solbiati L, Livraghi T: Tumor ablation with radio-frequency energy. Radiology 2000, 217(3):633-646.
- [4]Dupuy DE, Liu D, Hartfeil D, Hanna L, Blume JD, Ahrar K, Lopez R, Safran H, DiPetrillo T: Percutaneous radiofrequency ablation of painful osseous metastases: a multicenter American College of Radiology Imaging Network trial. Cancer 2010, 116(4):989-997. 15
- [5]Graham MV, Purdy JA, Emami B, Harms W, Bosch W, Lockett MA, Perez CA: Clinical dose-volume histogram analysis for pneumonitis after 3D treatment for non-small cell lung cancer (NSCLC). Int J Radiat Oncol Biol Phys 1999, 45(2):323-329. 1
- [6]Callstrom MR, Dupuy DE, Solomon SB, Beres RA, Littrup PJ, Davis KW, Paz-Fumagalli R, Hoffman C, Atwell TD, Charboneau JW, Schmit GD, Goetz MP, Rubin J, Brown KJ, Novotny PJ, Sloan JA: Percutaneous image-guided cryoablation of painful metastases involving bone: Multicenter trial. Cancer 2013, 119(5):1033-1041. 1
- [7]Jindal G, Friedman M, Locklin J, Wood BJ: Palliative radiofrequency ablation for recurrent prostate cancer. Cardiovasc Intervent Radiol 2006, 29(3):482-485.
- [8]Hiraki T, Mimura H, Gobara H, Sano Y, Fujiwara H, Date H, Kanazawa S: Repeat radiofrequency ablation for local progression of lung tumors: does it have a role in local tumor control? J Vasc Interv Radiol 2008, 19(5):706-711.