Antifeedant, larvicidal and growth inhibitory bioactivities of novel polyketide metabolite isolated from Streptomyces sp. AP-123 against Helicoverpa armigera and Spodoptera litura

BMC Microbiology

Sun-Ju Kim¹  Chinnasamy Muthukumar²  Veeramuthu Duraipandiyan²  Valsalam Saritha³  Naif Abdullah Al-Dhabi²  Mariadhas Valan Arasu³ 

[1] Department of Bio-Environmental Chemistry, Chungnam National University, 99 Daehak-Ro, Yuseong-Gu, Daejeon 305-764, Republic of Korea;Department of Botany and Microbiology, Addiriyah Chair for Environmental Studies, College of Science, King Saud University, P. O. Box 2455, Riyadh, 11451, Saudi Arabia;Global Research Centre for Biotechnology, Taramani, Chennai, India

关键词: Spodoptera litura;    Helicoverpa armigera;    Larvicidal;    Antifeedant;    Polyketide metabolite;    Streptomyces sp. AP-123;   

Others  :  1143722
DOI  :  10.1186/1471-2180-13-105

 received in 2012-11-21, accepted in 2013-04-30,  发布年份 2013

【 摘 要 】

Background

Considerable attention has been paid to actinomycetes, especially the secondary metabolites obtained from Streptomyces species, as the best alternatives to chemicals as biological control agents for polyphagous pests such as Helicoverpa armigera and Spodoptera litura. On the basis of their novel biocontrol attributes, novel polyketide metabolite isolated from marine Streptomyces sp. AP-123 exhibited significant antifeedant, larvicidal and growth inhibitory activities against polyphagous pests.

Results

Leaf disc no-choice method was used for the insect bioassay. The polyketide metabolite presented significant antifeedant activities against H. armigera (78.51%) and S. litura (70.75%) at 1000 ppm concentration. The metabolite also exhibited high larvicidal activities against H. armigera (63.11%) and S. litura (58.22%) and the LC₅₀ values were 645.25 ppm for H. armigera and 806.54 ppm for S. litura. The metabolite also prolonged the larval–pupal duration of the insects at all the tested concentrations.

Conclusions

The activities of the polyketide metabolite were concentration dependent for both the insects therefore it could be used as an agent to prepare new pesticidal formulations.

【 授权许可】

   
2013 Arasu et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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