Respiratory viruses within homeless shelters in Marseille, France

BMC Research Notes

Philippe Brouqui¹  Remi Charrel¹  Sekene Badiaga¹  Samir Benkouiten¹  Nicolas Salez¹  Simon-djamel Thiberville¹ 

[1] Faculté de médecine, Institut Hospitalo-Universitaire des Maladies Infectieuses et Tropicales URMITE CNRS IRD UMR 6236/198, 27 bd Jean MOULIN, Marseille 13005, France

关键词: Homeless persons;    Asymptomatic infections;    Respiratory syncytial virus;    Coronavirus;    Metapneumovirus;    Rhinovirus;    Influenza virus;    Respiratory tract disease;   

Others  :  1134595
DOI  :  10.1186/1756-0500-7-81

 received in 2013-07-18, accepted in 2014-01-30,  发布年份 2014

【 摘 要 】

Background

Homeless shelters are identified as places where humans are at high risk of acquiring respiratory disease. We previously reported the prevalence of the main respiratory diseases affecting a population of homeless in Marseille, France. Here, we investigated the prevalence of 10 respiratory viruses in a similar homeless population during 2 successive winter seasons.

Findings

Following a clinical examination, we collected nasal specimens from which the RT-PCR detection of 10 respiratory viruses was performed through snapshot investigations. Among the 265 patients included, 150 (56.6%) reported at least one respiratory symptom of which 13 (8.7%) had positive swabs for at least one respiratory virus, and 115 patients reported any respiratory symptom of which 10 (8.7%) had positive swabs for respiratory virus. Overall, 23 patients had positive swabs for at least one respiratory virus. Human rhinovirus (HRV) was the predominant virus (13 isolates) followed by enteroviruses (3), human metapneumovirus (2), human coronavirus OC43 (2), 229E virus (2) and human respiratory syncytial virus subtype B (1). Among the patients infected with HRV, 10 were collected during the same snapshot.

Conclusions

Although one half of the patients reported respiratory symptoms, the prevalence of respiratory viruses was within the range of that previously described in adult asymptomatic patients outside the homeless community. Most HRV-positive swabs were collected during the same snapshot suggesting a local outbreak. No influenza viruses were found despite the fact that one half of the patients were investigated during the peak of the seasonal influenza epidemic in Marseille.

【 授权许可】

   
2014 Thiberville et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

【 参考文献 】

• [1]Rossi PH, Wright JD, Fisher GA, Willis G: The urban homeless: estimating composition and size. Science 1987, 235:1336-1341.
• [2]Snyder LD, Eisner MD: Obstructive lung disease among the urban homeless. Chest 2004, 125:1719-1725.
• [3]Laurenti P, Bruno S, Quaranta G, La Torre G, Cairo AG, Nardella P, Delogu G, Fadda G, Pirronti T, Geraci S, et al.: Tuberculosis in sheltered homeless population of rome: an integrated model of recruitment for risk management. Sci World J 2012, 2012:396302.
• [4]Badiaga S, Richet H, Azas P, Zandotti C, Rey F, Charrel R, Benabdelkader El H, Drancourt M, Raoult D, Brouqui P: Contribution of a shelter-based survey for screening respiratory diseases in the homeless. Eur J Pub Health 2009, 19:157-160.
• [5]Rodwell TC, Robertson AM, Aguirre N, Vera A, Anderson CM, Lozada R, Chait L, Schooley RT, Zhang XQ, Strathdee SA: Pandemic (H1N1) 2009 surveillance in marginalized populations, Tijuana, Mexico. Emerg Infect Dis 2010, 16:1292-1295.
• [6]Thiberville SD, Ninove L, Vu Hai V, Botelho-Nevers E, Gazin C, Thirion L, Salez N, de Lamballerie X, Charrel R, Brouqui P: The viral etiology of an influenza-like illness during the 2009 pandemic. J Med Virol 2012, 84:1071-1079.
• [7]Graat JM, Schouten EG, Heijnen ML, Kok FJ, Pallast EG, de Greeff SC, Dorigo-Zetsma JW: A prospective, community-based study on virologic assessment among elderly people with and without symptoms of acute respiratory infection. J Clin Epidemiol 2003, 56:1218-1223.
• [8]Sanghavi SK, Bullotta A, Husain S, Rinaldo CR: Clinical evaluation of multiplex real-time PCR panels for rapid detection of respiratory viral infections. J Med Virol 2012, 84:162-169.
• [9]van Gageldonk-Lafeber AB, Heijnen ML, Bartelds AI, Peters MF, van der Plas SM, Wilbrink B: A case-control study of acute respiratory tract infection in general practice patients in The Netherlands. Clin Infect Dis 2005, 41:490-497.
• [10]Feikin DR, Njenga MK, Bigogo G, Aura B, Aol G, Audi A, Jagero G, Muluare PO, Gikunju S, Nderitu L, et al.: Etiology and incidence of viral and bacterial acute respiratory illness among older children and adults in rural western Kenya, 2007-2010. PloS one 2012, 7:e43656.
• [11]Peltola V, Waris M, Osterback R, Susi P, Ruuskanen O, Hyypia T: Rhinovirus transmission within families with children: incidence of symptomatic and asymptomatic infections. J Infect Dis 2008, 197:382-389.
• [12]Guthmann J: Enquête nationale de couverture vaccinale, France, janvier 2011. Couverture vaccinale contre la grippe saisonnière dans les groupes cibles et mesure de l’efficacité vaccinale. Couverture vaccinale par les vaccins diphtérie-tétanos-poliomyélite (dTP) et antipneumococcique chez les personnes âgées de 65 ans et plus. Book Enquête nationale de couverture vaccinale, France, janvier 2011. Couverture vaccinale contre la grippe saisonnière dans les groupes cibles et mesure de l’efficacité vaccinale. Couverture vaccinale par les vaccins diphtérie-tétanos-poliomyélite (dTP) et antipneumococcique chez les personnes âgées de 65 ans et plus 2011.
• [13]Jefferson T, Del Mar CB, Dooley L, Ferroni E, Al-Ansary LA, Bawazeer GA, van Driel ML, Nair S, Jones MA, Thorning S, Conly JM: Physical interventions to interrupt or reduce the spread of respiratory viruses. Cochrane Database Syst Rev 2011, (7):CD006207. DOI: 10.1002/14651858.CD006207.pub4.