Intra- and interobserver variability of language mapping by navigated transcranial magnetic brain stimulation

BMC Neuroscience

Sandro M Krieg²  Florian Ringel²  Bernhard Meyer²  Alexander Hapfelmeier¹  Theresa Hauck²  Nico Sollmann² 

[1] Institute of Medical Statistics and Epidemiology, Technische Universität München, Ismaninger Str. 22, 81675 Munich, Germany;Department of Neurosurgery, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675 Munich, Germany

关键词: Object naming;    Navigated brain stimulation;    Transcranial magnetic stimulation;    Language;    Cortical mapping;   

Others  :  1131184
DOI  :  10.1186/1471-2202-14-150

 received in 2013-09-09, accepted in 2013-11-27,  发布年份 2013

【 摘 要 】

Background

Repetitive navigated transcranial magnetic stimulation (rTMS) has been used for studying language organization in healthy volunteers and patients, and to detect cortical areas involved in language processing. However, little is known about the reliability of this method. To determine the reliability of rTMS language mapping, we conducted both an interobserver and an intraobserver investigation.

Methods

Ten right-handed healthy subjects underwent language mapping by rTMS and the same object-naming task three times. Intraobserver and interobserver reliability of seven different error types were tested by two investigators. Analysis was performed blinded to the previous results and stimulated cortical sites.

Results

Overall, the results of both the interobserver and the intraobserver investigations show variable accordance. This is demonstrated by comparing the error rates of all different error types of the three examinations. Considering the most important error type, “no response”, there is only small variability in inter- and intraobserver mapping.

Conclusions

With our current protocol, interobserver and intraobserver comparisons only corresponded partially. Thus, although rTMS seems a promising method for preoperative planning as well as neuropsychological research, the current protocol needs further improvement.

【 授权许可】

   
2013 Sollmann et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

【 参考文献 】

• [1]Indefrey P: The spatial and temporal signatures of word production components: a critical update. Front Psychol 2011, 2:255.
• [2]McGraw P, Mathews VP, Wang Y, Phillips MD: Approach to functional magnetic resonance imaging of language based on models of language organization. Neuroimaging Clin N Am 2001, 11(2):343-353.
• [3]Hund-Georgiadis M, Lex U, von Cramon DY: Language dominance assessment by means of fMRI: contributions from task design, performance, and stimulus modality. J Magn Reson Imaging 2001, 13(5):668-675.
• [4]Vigneau M, Beaucousin V, Herve PY, Duffau H, Crivello F, Houde O, Mazoyer B, Tzourio-Mazoyer N: Meta-analyzing left hemisphere language areas: phonology, semantics, and sentence processing. Neuroimage 2006, 30(4):1414-1432.
• [5]Wheat KL, Cornelissen PL, Sack AT, Schuhmann T, Goebel R, Blomert L: Charting the functional relevance of Broca’s area for visual word recognition and picture naming in Dutch using fMRI-guided TMS. Brain Lang 2013, 125(2):223-230.
• [6]Schuhmann T, Schiller NO, Goebel R, Sack AT: Speaking of which: dissecting the neurocognitive network of language production in picture naming. Cereb Cortex 2012, 22(3):701-709.
• [7]Ojemann G, Ojemann J, Lettich E, Berger M: Cortical language localization in left, dominant hemisphere. An electrical stimulation mapping investigation in 117 patients. J Neurosurg 1989, 71(3):316-326.
• [8]Haglund MM, Berger MS, Shamseldin M, Lettich E, Ojemann GA: Cortical localization of temporal lobe language sites in patients with gliomas. Neurosurgery 1994, 34(4):567-576. discussion 576
• [9]Sanai N, Mirzadeh Z, Berger MS: Functional outcome after language mapping for glioma resection. N Engl J Med 2008, 358(1):18-27.
• [10]Chang EF, Wang DD, Perry DW, Barbaro NM, Berger MS: Homotopic organization of essential language sites in right and bilateral cerebral hemispheric dominance. J Neurosurg 2011, 114(4):893-902.
• [11]Pascual-Leone A, Gates JR, Dhuna A: Induction of speech arrest and counting errors with rapid-rate transcranial magnetic stimulation. Neurology 1991, 41(5):697-702.
• [12]Wassermann EM, Blaxton TA, Hoffman EA, Berry CD, Oletsky H, Pascual-Leone A, Theodore WH: Repetitive transcranial magnetic stimulation of the dominant hemisphere can disrupt visual naming in temporal lobe epilepsy patients. Neuropsychologia 1999, 37(5):537-544.
• [13]Epstein CM, Lah JJ, Meador K, Weissman JD, Gaitan LE, Dihenia B: Optimum stimulus parameters for lateralized suppression of speech with magnetic brain stimulation. Neurology 1996, 47(6):1590-1593.
• [14]Lioumis P, Zhdanov A, Makela N, Lehtinen H, Wilenius J, Neuvonen T, Hannula H, Deletis V, Picht T, Makela JP: A novel approach for documenting naming errors induced by navigated transcranial magnetic stimulation. J Neurosci Methods 2012, 204(2):349-354.
• [15]Picht T, Krieg SM, Sollmann N, Rosler J, Niraula B, Neuvonen T, Savolainen P, Lioumis P, Makela JP, Deletis V, et al.: A comparison of language mapping by preoperative navigated transcranial magnetic stimulation and direct cortical stimulation during awake surgery. Neurosurgery 2013, 72(5):808-819.
• [16]Sollmann N, Picht T, Makela JP, Meyer B, Ringel F, Krieg SM: Navigated transcranial magnetic stimulation for preoperative language mapping in a patient with a left frontoopercular glioblastoma. J Neurosurg 2013, 118(1):175-179.
• [17]Sollmann N, Hauck T, Obermuller T, Hapfelmeier A, Meyer B, Ringel F, Krieg SM: Inter- and intraobserver variability in motor mapping of the hotspot for the abductor policis brevis muscle. BMC Neurosci 2013, 14(1):94. BioMed Central Full Text
• [18]Forster MT, Limbart M, Seifert V, Senft C: Test-Retest-Reliability of Navigated Transcranial Magnetic Stimulation of the Motor Cortex. Neurosurgery 2013. [Epub ahead of print]
• [19]Krieg SM, Sollmann N, Hauck T, Ille S, Foerschler A, Meyer B, Ringel F: Functional language shift to the right hemisphere in patients with language-eloquent brain tumors. PLoS One 2013, 8(9):e75403.
• [20]Salmelin R, Helenius P, Service E: Neurophysiology of fluent and impaired reading: a magnetoencephalographic approach. J Clin Neurophysiol 2000, 17(2):163-174.
• [21]Krieg SM, Shiban E, Buchmann N, Gempt J, Foerschler A, Meyer B, Ringel F: Utility of presurgical navigated transcranial magnetic brain stimulation for the resection of tumors in eloquent motor areas. J Neurosurg 2012, 116(5):994-1001.
• [22]Picht T, Mularski S, Kuehn B, Vajkoczy P, Kombos T, Suess O: Navigated transcranial magnetic stimulation for preoperative functional diagnostics in brain tumor surgery. Neurosurgery 2009, 65(6 Suppl):93-98.
• [23]Epstein CM: Transcranial magnetic stimulation: language function. J Clin Neurophysiol 1998, 15(4):325-332.
• [24]Corina DP, Loudermilk BC, Detwiler L, Martin RF, Brinkley JF, Ojemann G: Analysis of naming errors during cortical stimulation mapping: implications for models of language representation. Brain Lang 2010, 115(2):101-112.
• [25]Corina DP, Gibson EK, Martin R, Poliakov A, Brinkley J, Ojemann GA: Dissociation of action and object naming: evidence from cortical stimulation mapping. Hum Brain Mapp 2005, 24(1):1-10.
• [26]Lin LI: A concordance correlation coefficient to evaluate reproducibility. Biometrics 1989, 45(1):255-268.
• [27]Talacchi A, Santini B, Casartelli M, Monti A, Capasso R, Miceli G: Awake surgery between art and science. Part II: language and cognitive mapping. Funct Neurol 2013, 28(3):223-229.
• [28]Duffau H, Moritz-Gasser S, Mandonnet E: A re-examination of neural basis of language processing: proposal of a dynamic hodotopical model from data provided by brain stimulation mapping during picture naming. Brain Lang 2013. [Epub ahead of print]
• [29]Ungerleider LG, Doyon J, Karni A: Imaging brain plasticity during motor skill learning. Neurobiol Learn Mem 2002, 78(3):553-564.
• [30]Pascual-Leone A, Nguyet D, Cohen LG, Brasil-Neto JP, Cammarota A, Hallett M: Modulation of muscle responses evoked by transcranial magnetic stimulation during the acquisition of new fine motor skills. J Neurophysiol 1995, 74(3):1037-1045.
• [31]Rijntjes M, Weiller C: Recovery of motor and language abilities after stroke: the contribution of functional imaging. Prog Neurobiol 2002, 66(2):109-122.
• [32]Munte TF, Altenmuller E, Jancke L: The musician’s brain as a model of neuroplasticity. Nat Rev Neurosci 2002, 3(6):473-478.
• [33]Draganski B, Gaser C, Kempermann G, Kuhn HG, Winkler J, Buchel C, May A: Temporal and spatial dynamics of brain structure changes during extensive learning. J Neurosci 2006, 26(23):6314-6317.