BMC Public Health | |
Implementation of a universal rotavirus vaccination program: comparison of two delivery systems | |
Scott A Halperin3  Joanne M Langley3  Corinne Rowswell1  Donna MacDougall2  Beth A Halperin3  Anne Neatby1  Carolyn Sanford1  Mitchell Zelman1  | |
[1] Department of Health and Wellness, Charlottetown, Prince Edward Island, Canada;School of Nursing, Saint Francis Xavier University, Antigonish, Nova Scotia, Canada;IWK Health Centre, Halifax, Nova Scotia, Canada | |
关键词: Program evaluation; Immunization delivery models; Immunization program; Rotavirus vaccine; Rotavirus infection; | |
Others : 1128073 DOI : 10.1186/1471-2458-14-908 |
|
received in 2014-05-10, accepted in 2014-08-26, 发布年份 2014 | |
【 摘 要 】
Background
Rotavirus vaccine is recommended for all infants in Canada. To evaluate the logistics of implementing a universal rotavirus vaccination program, we compared the effectiveness of program implementation in jurisdictions with either a physician-administered or public health nurse-administered program.
Methods
All infants born between October 1, 2010 and September 30, 2012 in Prince Edward Island and Nova Scotia’s Capital District Health Authority were eligible for the vaccination program. A universal rotavirus vaccination program was implemented and delivered in public health clinics in Prince Edward Island and in physicians’ offices in Nova Scotia.
Results
Engagement of vaccinators in delivery of the universal vaccination program was more successful in Prince Edward Island than in Nova Scotia. Vaccine coverage rates rose rapidly in Prince Edward Island, exceeding 90% for both doses within 3 months and remaining at those levels over the two-year program. In contrast, coverage rates in Nova Scotia rose more slowly and never exceeded 40% during the two years. Access to coverage data was more timely and accurate in Prince Edward Island than Nova Scotia.
Conclusion
A universal rotavirus vaccination program delivered through public health clinics achieved more rapid and higher levels of coverage than a program administered through physicians’ offices.
Trial registration
【 授权许可】
2014 Zelman et al.; licensee BioMed Central Ltd.
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
20150222083355559.pdf | 289KB | download | |
Figure 1. | 47KB | Image | download |
【 图 表 】
Figure 1.
【 参考文献 】
- [1]World Health Organization: Estimated rotavirus deaths for children under 5 years of age. 2014. http://www.who.int/immunization/monitoring_surveillance/burden/estimates/rotavirus/en/index.html webcite. Accessed 28 January 2014.
- [2]Parashar UD, Burton A, Lanata C, Boschi-Pinto C, Shibuya K, Steele D, Birmingham M, Glass RI: Global mortality associated with rotavirus disease among children in 2004. J Infect Dis 2009, 200:S9-S15.
- [3]Tate JE, Burton AH, Boschi-Pinto C, Steele AD, Duque J, Parashar UD, WHO-coordinated Global Rotavirus Surveillance Network: 2008 estimate of worldwide rotavirus-associated mortality in children younger than 5 years before the introduction of universal rotavirus vaccination programmes: a systematic review and meta-analysis. Lancet 2012, 12:136-141.
- [4]Bernstein DI: Rotavirus overview. Ped Infect Dis J 2009, 29:S50-S53.
- [5]Senecal M, Brisson M, Lebel MH, Yaremko J, Wong R, Gallant LA: Measuring the impact of rotavirus acute gastroenteritis (MIRAGE): a prospective community-based study. Can J Infect Dis Med Microbiol 2008, 19:397-404.
- [6]Le Saux N, Bettinger JA, Halperin SA, Vaudry W, Scheifele DW, for members of the Canadian Immunization Monitoring Program, Active (IMPACT): Substantial morbidity for hospitalized children with community-acquired rotavirus infections: 2005-2007 IMPACT surveillance in Canadian hospitals. Ped Infect Dis J 2010, 29:879-892.
- [7]Clark HF, Offit PA, Ellis RW, Eiden JJ, Krah D, Shaw AR, Pichichero M, Treanor JJ, Borian FE, Bell LM, Plotkin SA: The development of multivalent bovine rotavirus (strain WC3) reassortant vaccine for infants. J Infect Dis 1996, 174:S73-S80.
- [8]Bernstein DI, Sack DA, Rothstein E, Reisinger K, Ward RL: Efficacy of live, attenuated human rotavirus vaccine 89-12 in infants. Lancet 1999, 354:287-290.
- [9]Vesikari T, Matson DO, Dennehy P, Van Damme P, Santosham M, Rodriguez Z, Dallas MJ, Heyse JF, Goveia MG, Black SB, Shinefield HR, Christie CD, Ylitalo S, Itzler RF, Coia ML, Onorato MT, Adeyi BA, Marshall GS, Gothefors L, Campens D, Karvonen A, Watt JP, O'Brien KL, DiNubile MJ, Clark HF, Boslego JW, Offit PA, Heaton PM, Rotavirus Efficacy and Safety Trial (REST) Study Team: Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine. N Engl J Med 2006, 354:23-33.
- [10]Vesikari T, Karvonen A, Prymula R, Schuster V, Tejedor JC, Cohen R, Meurice F, Han HH, Damaso S, Bouckenooghe A: Efficacy of human rotavirus vaccine against rotavirus gastroenteritis during the first 2 years of life in European infants: randomized, double-blind controlled study. Lancet 2007, 370:1757-1763.
- [11]National Advisory Committee on Immunization: Rotavirus Vaccine. Canadian Immunization Guide 2014. http://www.phac-aspc.gc.ca/publicat/cig-gci/p04-rot-eng.php webcite. Accessed 30 January 2014
- [12]Canadian Immunization Committee: Recommendations for rotavirus immunization programs. 2014. http://www.phac-aspc.gc.ca/publicat/ccdr-rmtc/14vol40/dr-rm40-02/dr-rm40-02-rota-eng.php webcite. Accessed 30 January 2014
- [13]Fisman DN, Chan CH, Lowcock E, Naus M, Lee V: Effectiveness and cost-effectiveness of pediatric rotavirus vaccination in British Columbia: a model-based evaluation. Vaccine 2012, 30:7601-7607.
- [14]Coyle D, Coyle K, Bettinger JA, Halperin SA, Vaudry W, Scheifele DW, Le Saux N: Cost effectiveness of infant vaccination for rotavirus in Canada. Can J Infect Dis Med Microbiol 2012, 23:71-77.
- [15]Statistics Canada: Births and total fertility rate, by province and territory. 2014. http://www.statcan.gc.ca/tables-tableaux/sum-som/l01/cst01/hlth85a-eng.htm webcite. Accessed 9 February 2014.
- [16]Statistics New Brunswick: Live Births by Age of Mother and Health Region of Residence, New Brunswick. 2011. http://www.snb.ca/e/1000/1000-01/pdf-2011/T7-1B.pdf webcite. Accessed 9 February 2014
- [17]Erickson LJ, De Wals P, Farand L: An analytical framework for immunization programs in Canada. Vaccine 2005, 23:2470-2476.
- [18]Parashar UD, Alexander JP, Glass RI: Prevention of rotavirus gastroenteritis among infants and children. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 2006, 55(RR12):1-13.
- [19]Centers for Disease Control and Prevention: National, State, and Local Area Vaccination Coverage Among Children Aged 19–35 Months — United States, 2012. MMWR Morb Mortal Wkly Rep 2013, 62:733-740.
- [20]Centers for Disease Control and Prevention: Recommendations of the Advisory Committee on Immunization Practice (ACIP). Quadrivalent human papillomavirus vaccine. MMWR Recomm Rep 2007, 56(RR02):1-24.
- [21]Centers for Disease Control and Prevention: National Immunization Survey-Teen Data (Adolescents-Teens 13-17 years of age. 2014. http://www.cdc.gov/vaccines/imz-managers/coverage/nis/teen/index.html webcite. Accessed 1 March 2014.
- [22]Centers for Disease Control and Prevention: Vaccine-specific coverage among children 19-35 months, National Immunization Survey, 1994-2012. 2014. http://www.dcd.gov/vaccines/imz-managers/coverage/nis/child/index.html webcite. Accessed 1 March 2014
- [23]Rapola S: National immunization program in Finland. Int J Circumpolar Health 2007, 66:382-389.
- [24]Leino T, Ollgren J, Salo H, Tiihonen P, Kilpi T: First year experience of rotavirus immunization program in Finland. Vaccine 2012, 31:176-182.
- [25]Population Health Assessment and Surveillance: School-based immunization coverage in Nova Scotia: 2008-09 to 2011-12. Nova Scotia: Department of Health and Wellness; 2013. http://novascotia.ca/dhw/populationhealth/ webcite. Accessed 1 March 2014
- [26]Public Health England: Annual vaccine coverage statistics: England. NHS Immunisation Statistics England 2012-13 2014. http://www.hscic.gov.uk/catalogue/PUB11665/nhs-immu-stat-eng-2012-13-rep.pdf webcite. Accessed 1 March 2014
- [27]Amirthalingam G, Gupta S, Campbell H: Pertussis immunisation and control in England and Wales, 1957 to 2012: a historical review. Euro Surveill 2013, 18:1-8.