The Stockpile Stewardship Program (SSP) is a highly integrated technical program for maintaining the safety, security, survivability, and reliability of the U.S. nuclear weapons stockpile. The SSP uses past nuclear test data, current and future non-nuclear test data, computational modeling and simulation, and experimental facilities to advance understanding of nuclear weapons and to resolve urgent problems of national interest related to the stockpile. The results of stockpile surveillance and experimental research, combined with modeling and simulation, support the development of engineering programs and an appropriately scaled production capability. The Advanced Simulation and Computing (ASC) Campaign is a cornerstone of the SSP. It provides simulation capabilities and computational resources to: (a) support the annual stockpile assessment and certification process (b) study advanced nuclear-weapons design, engineering and manufacturing processes (c) analyze accident scenarios and weapons aging (d) support stockpile Life Extension Programs (LEP) and the resolution of Significant Finding Investigations (SFIs). This requires a balanced program, including technical staff, hardware, simulation software, and computer science solutions.