Associations between childhood maltreatment and emotion processing biases in major depression: results from a dot-probe task

BMC Psychiatry

Thomas Suslow²  Anette Kersting¹  Udo Dannlowski²  Vivien Günther¹ 

[1] Department of Psychosomatic Medicine and Psychotherapy, University of Leipzig, Semmelweisstr. 10, Leipzig, 04103, Germany;Department of Psychiatry, University of Munster, Munster, Germany

关键词: Depression;    Perception;    Attention;    Facial emotions;    Childhood maltreatment;   

Others  :  1216026
DOI  :  10.1186/s12888-015-0501-2

 received in 2014-12-04, accepted in 2015-05-15,  发布年份 2015

【 摘 要 】

Background

Childhood maltreatment is considered an important risk factor for the development of major depression. Research indicates an association between childhood adversity and altered emotion processing. Depression is characterized by mood-congruent cognitive biases, which play a crucial role in symptom persistence and recurrence. However, whether attentional biases in adult major depression are associated with experienced childhood neglect or abuse remains unclear.

Methods

A sample of 45 patients suffering from major depression were recruited to examine correlations between maltreatment experienced during childhood and attentional biases to sad and happy facial expressions. Attention allocation was assessed using the dot-probe task and a history of childhood maltreatment was measured by means of the 25-item Childhood Trauma Questionnaire (CTQ).

Results

Our results indicate an association between childhood maltreatment and sustained attention toward sad facial expressions. This relationship was not confounded by severity of symptoms, age, verbal intelligence or more recent stressful experiences.

Conclusions

Our findings confirm the hypothesis that a mood-congruent bias in emotion processing observed in major depression is related to early traumatic experiences.

【 授权许可】

   
2015 Günther et al.

【 图 表 】

Fig. 1.

【 参考文献 】

• [1]Gilbert R, Widom CS, Browne K, Fergusson D, Webb E, Janson S: Burden and consequences of child maltreatment in high-income countries. Lancet 2009, 373:68-81.
• [2]Bernstein DP, Fink L, Handelsman L, Foote J, Lovejoy M, Wenzel K, et al.: Initial reliability and validity of a new retrospective measure of child abuse and neglect. Am J Psychiatry 1994, 151:1132-1136.
• [3]Chapman DP, Whitfield CL, Felitti VJ, Dube SR, Edwards VJ, Anda RF: Adverse childhood experiences and the risk of depressive disorders in adulthood. J Affect Disord 2004, 82:217-225.
• [4]Widom CS, DuMont K, Czaja SJ: A prospective investigation of major depressive disorder and co morbidity in abused and neglected children grown up. Arch Gen Psychiatry 2007, 64:49-56.
• [5]Alloy LB, Abramson LY, Smith JM, Gibb BE, Neeren AM: Role of Parenting and Maltreatment Histories in Unipolar and Bipolar Mood Disorders: Mediation by Cognitive Vulnerability to Depression. Clin Child Fam Psychol Rev 2006, 9:23-64.
• [6]Teicher MH, Samson JA: Childhood maltreatment and psychopathology: A case for ecophenotypic variants as clinically and neurobiologically distinct subtypes. Am J Psychiatry 2013, 170:1114-1133.
• [7]Gibb BE, Alloy LB, Abramson LY, Rose DT, Whitehouse WG, Donovan P, et al.: History of childhood maltreatment, negative cognitive styles, and episodes of depression in adulthood. Cogn Ther Res 2001, 25:425-446.
• [8]Rose DT, Abramson LY: Developmental predictors of depressive cognitive style: research and theory. In Developmental perspectives on depression. Edited by Cicchetti D, Toth SL. University of Rochester Press, Rochester, N.Y., USA; 1992:323-349.
• [9]Gibb BE, Abela JRZ: Emotional abuse, verbal victimization, and the development of children’s negative inferential styles and depressive symptoms. Cogn Ther Res 2008, 32:161-176.
• [10]Gibb BE, Alloy LB, Abramson LY, Marx BP: Childhood maltreatment and maltreatment‐specific inferences: A test of Rose and Abramson’s (1992) extension of the hopelessness theory. Cogn Emot 2003, 17:917-931.
• [11]Gibb BE, Alloy LB, Walshaw PD, Comer JS, Shen , Gail HC, et al.: Predictors of attributional style change in children. J Abnorm Child Psychol 2006, 34:408-422.
• [12]Hankin BL: Childhood Maltreatment and Psychopathology: Prospective Tests of Attachment, Cognitive Vulnerability, and Stress as Mediating Processes. Cogn Ther Res 2005, 29:645-671.
• [13]Gibb BE: Childhood maltreatment and negative cognitive styles: a quantitative and qualitative review. Clin Psychol Rev 2002, 22:223-246.
• [14]Beck AT: The evolution of the cognitive model of depression and its neurobiological correlates. Am J Psychiatry 2008, 165:969-977.
• [15]Abramson LY, Metalsky GI, Alloy LB: Hopelessness depression: A theory-based subtype of depression. Psychol Rev 1989, 96:358-372.
• [16]Suslow T, Dannlowski U: Detection of facial emotion in depression. In Mood state and health. Edited by Clark AV. Nova Biomedical Books, New York; 2005:1-32.
• [17]Bistricky SL, Ingram RE, Atchley RA: Facial affect processing and depression susceptibility: Cognitive biases and cognitive neuroscience. Psychol Bull 2011, 137:998-1028.
• [18]Gollan JK, Pane HT, McCloskey MS, Coccaro EF: Identifying differences in biased affective information processing in major depression. Psychiatry Res 2008, 159:18-24.
• [19]Mogg K, Bradbury KE, Bradley BP: Interpretation of ambiguous information in clinical depression. Behav Res Ther 2006, 44:1411-1419.
• [20]Ridout N, Astell A, Reid I, Glen T, O’Carroll R: Memory bias for emotional facial expressions in major depression. Cogn Emot 2003, 17:101-122.
• [21]Yoon KL, Joormann J, Gotlib IH: Judging the intensity of facial expressions of emotion: depression-related biases in the processing of positive affect. J Abnorm Psychol 2009, 118:223-228.
• [22]Gotlib IH, Krasnoperova E, Neubauer Yue D, Joormann J: Attentional biases for negative interpersonal stimuli in clinical depression. J Abnorm Psychol 2004, 113:121-135.
• [23]MacLeod C, Mathews A, Tata P: Attentional bias in emotional disorders. J Abnorm Psychol 1986, 95:15-20.
• [24]Gotlib IH, Kasch KL, Traill S, Joormann J, Arnow BA, Johnson SL: Coherence and Specificity of Information-Processing Biases in Depression and Social Phobia. J Abnorm Psychol 2004, 113:386-398.
• [25]Joormann J, Gotlib IH: Selective attention to emotional faces following recovery from depression. J Abnorm Psychol 2007, 116:80-85.
• [26]Leyman L, De Raedt R, Schacht R, Koster EHW: Attentional biases for angry faces in unipolar depression. Psychol Med 2007, 37:393-402.
• [27]Arnone D, McKie S, Elliott R, Thomas EJ, Downey D, Juhasz G, et al.: Increased amygdala responses to sad but not fearful faces in major depression: relation to mood state and pharmacological treatment. Am J Psychiatry 2012, 169:841-850.
• [28]Sheline YI, Barch DM, Donnelly JM, Ollinger JM, Snyder AZ, Mintun MA: Increased amygdala response to masked emotional faces in depressed subjects resolves with antidepressant treatment: an fMRI study. Biol Psychiatry 2001, 50:651-658.
• [29]Stuhrmann A, Dohm K, Kugel H, Zwanzger P, Redlich R, Grotegerd D, et al.: Mood-congruent amygdala responses to subliminally presented facial expressions in major depression: associations with anhedonia. J Psychiatry Neurosci 2013, 38:249-258.
• [30]Suslow T, Konrad C, Kugel H, Rumstadt D, Zwitserlood P, Schöning S, et al.: Automatic mood-congruent amygdala responses to masked facial expressions in major depression. Biol Psychiatry 2010, 67:155-160.
• [31]Victor TA, Furey ML, Fromm SJ, Ohman A, Drevets WC: Relationship between amygdala responses to masked faces and mood state and treatment in major depressive disorder. Arch Gen Psychiatry 2010, 67:1128-1138.
• [32]Davis M, Whalen PJ: The amygdala: vigilance and emotion. Mol Psychiatry 2001, 6:13-34.
• [33]Vuilleumier P: The role of the human amygdala in perception and attention. In The human amygdala. Edited by Whalen PJ, Phelps EA. Guilford Press, New York; 2009:220-249.
• [34]Phan KL, Wager T, Taylor SF, Liberzon I: Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRI. NeuroImage 2002, 16:331-348.
• [35]Phillips ML, Drevets WC, Rauch SL, Lane R: Neurobiology of emotion perception II: implications for major psychiatric disorders. Biol Psychiatry 2003, 54:515-528.
• [36]Dannlowski U, Ohrmann P, Bauer J, Kugel H, Arolt V, Heindel W, et al.: Amygdala reactivity to masked negative faces is associated with automatic judgmental bias in major depression: a 3 T fMRI study. J Psychiatry Neurosci 2007, 32:423-429.
• [37]Grant MM, Cannistraci C, Hollon SD, Gore J, Shelton R: Childhood trauma history differentiates amygdala response to sad faces within MDD. J Psychiat Res 2011, 45:886-895.
• [38]Van Harmelen A, Van Tol M, Demenescu LR, Van der Wee NJA, Veltman DJ, Aleman A, et al.: Enhanced amygdala reactivity to emotional faces in adults reporting childhood emotional maltreatment. Soc Cogn Affect Neurosci 2013, 8:362-369.
• [39]Dannlowski U, Kugel H, Huber F, Stuhrmann A, Redlich R, Grotegerd D, et al.: Childhood maltreatment is associated with an automatic negative emotion processing bias in the amygdala. Hum Brain Mapp 2013, 34:2899-2909.
• [40]Gibb BE, Schofield CA, Coles ME: Reported history of childhood abuse and young adults’ information-processing biases for facial displays of emotion. Child Maltreat 2009, 14:148-156.
• [41]Pollak SD, Sinha P: Effects of early experience on children’s recognition of facial displays of emotion. Dev Psychol 2002, 38:784-791.
• [42]Pine DS, Mogg K, Bradley BP, Montgomery L, Monk CS, McClure E, et al.: Attention bias to threat in maltreated children: implications for vulnerability to stress-related psychopathology. Am J Psychiatry 2005, 162:291-296.
• [43]Fani N, Bradley-Davino B, Ressler KJ, McClure-Tone EB: Attention bias in adult survivors of childhood maltreatment with and without posttraumatic stress disorder. Cogn Ther Res 2011, 35:57-67.
• [44]Mathews A, MacLeod C: Cognitive vulnerability to emotional disorders. Annu Rev Clin Psychol 2005, 1:167-195.
• [45]Peckham AD, McHugh RK, Otto MW: A meta-analysis of the magnitude of biased attention in depression. Depress Anxiety 2010, 27:1135-1142.
• [46]Romens SE, Pollak SD: Emotion regulation predicts attention bias in maltreated children at-risk for depression. J Child Psychol Psychiatry 2012, 53:120-127.
• [47]Armstrong T, Olatunji BO: Eye tracking of attention in the affective disorders: a meta-analytic review and synthesis. Clin Psychol Rev 2012, 32:704-723.
• [48]Koster EHW, De Raedt R, Goeleven E, Franck E, Crombez G: Mood-congruent attentional bias in dysphoria: maintained attention to and impaired disengagement from negative information. Emotion 2005, 5:446-455.
• [49]Wittchen H, Wunderlich U, Gruschwitz S, Zaudig M: SKID-I. Strukturiertes Klinisches Interview für DSM-IV. Hogrefe, Göttingen; 1997.
• [50]Hautzinger M, Keller F, Kühner C: BDI-II. Beck-Depressions-Inventar. Revision. Frankfurt/Main, Pearson; 2009.
• [51]CIPS Collegium Internationale Psychiatriae Scalarum: Internationale Skalen für Psychiatrie. 5th edition. Beltz Test GmbH, Göttingen; 2005.
• [52]Margraf J, Ehlers A: Beck Angst-Inventar. Frankfurt/Main, Pearson; 2007.
• [53]Bader K, Hänny C, Schäfer V, Neuckel A, Kuhl C: Childhood trauma questionnaire – psychometrische Eigenschaften einer deutschsprachigen Version. Z Klin Psychol Psych 2009, 38:223-230.
• [54]Bernstein DP, Fink L: Childhood trauma questionnaire: a retrospective self-report. The Psychological Corporation, San Antonio, TX; 1998.
• [55]Bernstein DP, Stein JA, Newcomb MD, Walker E, Pogge D, Ahluvalia T, et al.: Development and validation of a brief screening version of the childhood trauma questionnaire. Child Abuse Negl 2003, 27:169-190.
• [56]Cohen S, Williamson GM: Perceived stress in a probability sample of the United States. In The social psychology of health. Edited by Spacapan S, Oskamp S. Sage, Newbury Park, CA; 1988:31-67.
• [57]Cohen S, Kamark T, Mermelstein R: A global measure of perceived stress. J Health Soc Behav 1983, 24:385-396.
• [58]Brugha TS, Cragg D: The list of threatening experiences: the reliability and validity of a brief life events questionnaire. Acta Psychiatr Scand 1990, 82:77-81.
• [59]Brugha TS, Bebbington P, Tennant C, Hurry J: The list of threatening experiences: a subset of 12 life event categories with considerable long-term contextual threat. Psychol Med 1985, 15:189-194.
• [60]Lehrl S: Manual zum MWT-B. 5th edition. Balingen, Spitta-Verlag; 2005.
• [61]Lundqvist D, Flykt A, Öhman A: The Karolinska directed emotional faces-KDEF. 1998.
• [62]Mogg K, Bradley BP, Williams R: Attentional bias in anxiety and depression: the role of awareness. Br J Clin Psychol 1995, 34:17-36.
• [63]Lee IA, Preacher KJ: Calculation for the test of the difference between two dependent correlations with one variable in common. 2013.
• [64]Wingenfeld K, Spitzer C, Mensebach C, Grabe HJ, Hill A, Gast U, et al.: Die deutsche Version des Childhood Trauma Questionnaire (CTQ): erste Befunde zu den psychometrischen Kennwerten. Psychother Psychosom Med Psychol 2010, 60:442-450.
• [65]Beevers CG, Scott WD, McGeary C, McGeary JE: Negative cognitive response to a sad mood induction: associations with polymorphisms of the serotonin transporter (5-HTTLPR) gene. Cogn Emot 2009, 23:726-738.
• [66]Scher CD, Ingram RE, Segal ZV: Cognitive reactivity and vulnerability: empirical evaluation of construct activation and cognitive diatheses in unipolar depression. Clin Psychol Rev 2005, 25:487-510.
• [67]Segal ZV, Ingram RE: Mood priming and construct activation in tests of cognitive vulnerability to unipolar depression. Clin Psychol Rev 1994, 14:663-695.
• [68]Beevers CG: Cognitive vulnerability to depression: a dual process model. Clin Psychol Rev 2005, 25:975-1002.
• [69]Brockmeyer T, Pfeiffer N, Grosse Holtforth M, Zimmermann J, Kämmerer A, Friederich H, et al.: Mood regulation and cognitive reactivity in depression vulnerability. Cogn Ther Res 2012, 36:634-642.
• [70]Wells TT, Vanderlind WM, Selby EA, Beevers CG: Childhood abuse and vulnerability to depression: cognitive scars in otherwise healthy young adults. Cogn Emot 2013, 28:821-833.
• [71]Padilla Paredes P, Calvete E: Cognitive vulnerabilities as mediators between emotional abuse and depressive symptoms. J Abnorm Child Psychol 2014, 42:743-753.
• [72]Dannlowski U, Stuhrmann A, Beutelmann V, Zwanzger P, Lenzen T, Grotegerd D, et al.: Limbic scars: long-term consequences of childhood maltreatment revealed by functional and structural magnetic resonance imaging. Biol Psychiatry 2012, 71:286-293.
• [73]Elliott R, Zahn R, Deakin J, William F, Anderson IM: Affective cognition and its disruption in mood disorders. Neuropsychopharmacol 2010, 36:153-182.
• [74]Hamilton JP, Gotlib IH: Neural substrates of increased memory sensitivity for negative stimuli in major depression. Biol Psychiatry 2008, 63:1155-1162.
• [75]Atchley RA, Ilardi SS, Young KM, Stroupe NN, O’Hare AJ, Bistricky SL, et al.: Depression reduces perceptual sensitivity for positive words and pictures. Cogn Emot 2012, 26:1359-1370.
• [76]McCabe SB, Gotlib IH: Selective attention and clinical depression: performance on a deployment-of-attention task. J Abnorm Psychol 1995, 104:241-245.
• [77]Suslow T, Junghanns K, Arolt V: Detection of facial expressions of emotions in depression. Percept Mot Skills 2001, 92:857-868.
• [78]Van Harmelen A, Jong PJ D, Glashouwer KA, Spinhoven P, Penninx BWJH, Elzinga BM: Child abuse and negative explicit and automatic self-associations: the cognitive scars of emotional maltreatment. Behav Res Ther 2010, 48:486-494.
• [79]Kessler RC, Berglund P, Demler O, Jin R, Koretz D, Merikangas KR, et al.: The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA 2003, 289:3095-3105.
• [80]Sackeim HA: The definition and meaning of treatment-resistant depression. J Clin Psychiatry 2001, 62(suppl 16):10-17.
• [81]Bernstein DP, Ahluvalia T, Pogge D, Handelsman L: Validity of the Childhood Trauma Questionnaire in an adolescent psychiatric population. J Am Acad Child Psychiatry 1997, 36:340-348.
• [82]Spinhoven P, Penninx BW, Hickendorff M, Van H, Albert M, Bernstein DP, et al.: Childhood Trauma Questionnaire: factor structure, measurement invariance, and validity across emotional disorders. Psychol Assess 2014, 26:717-729.
• [83]Nanni V, Uher R, Danese A: Childhood maltreatment predicts unfavorable course of illness and treatment outcome in depression: a meta-analysis. Am J Psychiatry 2012, 169:141-151.