Strongyloides stercoralis is a cause of abdominal pain, diarrhea and urticaria in rural Cambodia

BMC Research Notes

Peter Odermatt³  Hanspeter Marti²  Sinuon Muth¹  Fabian Schär³  Sophanaroth Srey¹  Virak Khieu³ 

[1] National Centre for Parasitology, Entomology and Malaria Control, Ministry of Health, Phnom Penh, Cambodia;Medical and Diagnostics Department, Swiss Tropical and Public Health Institute, Basel, Switzerland;University of Basel, Basel, Switzerland

关键词: Cambodia;    Ivermectin;    Clinical symptoms;    Strongyloides stercoralis;   

Others  :  1142645
DOI  :  10.1186/1756-0500-6-200

 received in 2012-09-05, accepted in 2013-05-15,  发布年份 2013

【 摘 要 】

Background

We document clinical manifestations of 21 patients heavily infected with S. stercoralis (more than 250 larvae in a single Baermann test) from a community in rural Cambodia, both before and three weeks after ivermectin (200 μg/kg BW, single oral dose) treatment.

Findings

Out of 21 patients, 20 (95.2%), 18 (85.7%) and 14 (66.7%) reported frequent abdominal pain, diarrhea and periods of sensation of itching, respectively, during the previous six months; epigastric (11, 55.0%) and peri-umbilical (13, 65.0%) pains were most frequent. Five patients (23.8%) reported having experienced urticaria the week preceding the examination. One patient suffered from extended urticaria. Three weeks after treatment, most symptoms had been almost entirely resolved.

Conclusions

In rural communities of Cambodia, strongyloidiasis with high parasite load is endemic. It is associated with substantial symptoms and clinical signs, particularly abdominal pain, diarrhea and urticaria. Access to adequate diagnosis and treatment is a pressing issue that needs attention.

【 授权许可】

   
2013 Khieu et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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