Bone chips, fibrin glue, and osteogeneration following lateral suboccipital craniectomy: a case report

BMC Research Notes

Thomas Westermaier²  Ralf I Ernestus²  Almuth F Kessler²  Camelia M Monoranu¹  Thomas Linsenmann² 

[1] Departments of Neuropathology, University of Würzburg, Josef-Schneider-Str. 11, Würzburg D-97080, Germany;Departments of Neurosurgery, University of Würzburg, Josef-Schneider-Str. 11, Würzburg D-97080, Germany

关键词: Lateral suboccipital craniectomy;    Osteogeneration;    Fibrin glue;    Bone chips;   

Others  :  1140534
DOI  :  10.1186/1756-0500-6-523

 received in 2013-08-07, accepted in 2013-11-26,  发布年份 2013

【 摘 要 】

Background

Suboccipital craniectomy is a conventional approach for exploring cerebellopontine angle lesions. A variety of techniques have been successfully employed to reconstruct a craniectomy. This is the first report about the histological findings after performing a cranioplasty by using a mixture of autologous bone chips and human allogenic fibrin glue.

Case presentation

A 53-year-old German woman underwent left lateral suboccipital retrosigmoidal craniectomy for treatment of trigeminal neuralgia in 2008. Cranioplasty was perfomed by using a mixture of autologous bone chips and human allogenic fibrin glue. Due to recurrent neuralgia, a second left lateral suboccipital craniectomy was performed in 2012. The intraoperative findings revealed a complete ossification of the former craniotomy including widely mature trabecular bone tissue in the histological examination.

Conclusion

A mixture of autologous bone chips and human allogenic fibrin glue seems to provide sufficient bone-regeneration revealed by histological and neuroradiological examinations.

【 授权许可】

   
2013 Linsenmann et al.; licensee BioMed Central Ltd.

【 图 表 】

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【 参考文献 】

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