High prevalence of Helicobacter pylori infection in Behcet’s disease

BMC Gastroenterology

Akbar Rajaee¹  Mohammad Ali Nazarinia¹  Elham Aflaki¹  Mohammad Reza Ravanbod²  Kamran B Lankarani³ 

[1] Rheumatology Research Center, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran;Bushehr University of Medical Sciences, Bushehr, Islamic Republic of Iran;Health policy Research Center, Shiraz University of Medical Sciences, P.O. Box 71345–1414, Shiraz, Islamic Republic of Iran

关键词: Urea breath test;    Pathogenesis;    Behcet’s disease;    Helicobacter pylori;   

Others  :  855647
DOI  :  10.1186/1471-230X-14-58

 received in 2013-07-20, accepted in 2014-03-12,  发布年份 2014

【 摘 要 】

Background

Behcet’s disease (BD) is a multisystem disease of unknown etiology. There are several clues which may indicate an ethiopathogenesis role for Helicobacter pylori infection in this disease.

Methods

In a case control study in an out patient department, 48 patients with BD were compared to age, sex matched controls regarding presence of H. pylori infection by serology and urea breath test (UBT).

Results

Ongoing H. pylori infection was more prevalent among patients with BD using result of UBT with odds ratio of 3.1 (95% CI: 1.34 – 7.26, PV < 0.001).

Conclusion

H. pylori infection may have a role in the pathogenesis of BD.

【 授权许可】

   
2014 Lankarani et al.; licensee BioMed Central Ltd.

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