Influence of health behaviours on the incidence of infection and allergy in adolescents: the AFINOS cross-sectional study

BMC Public Health

Ascensión Marcos³  Oscar L Veiga²  Maria E Calle¹  Ana M Veses³  Sonia Gómez-Martínez³  David Martínez-Gómez²  Esther Nova³ 

[1] Department of Preventive Medicine and Public Health, Faculty of Medicine, Universidad Complutense de Madrid, Madrid, Spain;Department of Physical Education, Sport and Human Movement. Faculty of Teaching Training and Education, Universidad Autónoma de Madrid, Madrid, Spain;Immunonutrition Group, Institute of Food Science and Technology and Nutrition. ICTAN-CSIC, C/Jose Antonio Novais 10, 28040 Madrid, Spain

关键词: Leptin;    IgE;    Sleep;    Obesity;    Overweight;    Infection;    Healthy habits;    Allergy;   

Others  :  1161364
DOI  :  10.1186/1471-2458-14-19

 received in 2013-06-03, accepted in 2013-12-10,  发布年份 2014

【 摘 要 】

Background

Some health behaviours are liable to affect the incidence of allergies and/or common infections in young people; however, the extent and ways in which these might occur are mostly unknown. This study examines the association of health behaviours related to physical activity, sedentariness, diet and sleep with allergy and infection symptoms in adolescents, and also with biological markers that might mediate disease incidence.

Methods

The study comprised a total of 2054 adolescents (50.7% girls) from the Madrid region of Spain. The incidence of infection and allergy symptoms three months prior to the study was obtained from a self-administered questionnaire. Physical and sedentary activities, height and weight, food habits and sleep duration were also self-reported and their influence on infection and allergy incidence was assessed by logistic regression analysis. Blood biomarkers (IgE, eosinophil percentage, leptin, interleukin (IL)-2, IL-4, IL-5 and IL-10) were evaluated in a subsample of 198 subjects.

Results

Adequate sleep duration (OR = 0.79, 95%CI: 0.64 to 0.97) and unhealthy weight status (overweight/obesity) (OR = 1.35, 95%CI: 1.04-1.74) were independently associated with decreased and increased allergy incidence, respectively. No significant association was observed with infection incidence. IgE and leptin differed between adolescents with and without allergy symptoms. In regression models IgE was significantly associated with inadequate sleep duration and leptin with weight status.

Conclusion

Excess weight and inadequate sleep duration are independently associated with the incidence of allergy symptoms in adolescents. Adequate sleep duration and weight during adolescence might be relevant for a decreased risk of suffering allergy symptoms.

【 授权许可】

   
2014 Nova et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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