期刊论文详细信息
BMC Pediatrics
Adoption of the children’s obesity clinic’s treatment (TCOCT) protocol into another Danish pediatric obesity treatment clinic
Jens-Christian Holm3  Michael Gamborg2  Mette Valentiner1  Jesper Andersen3  Grete Teilmann3  Birgitte Højgaard1  Sebastian W Most1 
[1]The Children’s Obesity Clinic, Department of Pediatrics, Nordsjællands Hospital, Hillerød, Copenhagen University, Dyrehavevej 29, Hillerød, DK-3400, Denmark
[2]Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen, Denmark
[3]Institute of Internal Medicine, the Medical Faculty, University of Copenhagen, Copenhagen, Denmark
关键词: Treatment;    Puberty;    Obesity;    Child;    BMI;    Adolescence;   
Others  :  1138388
DOI  :  10.1186/s12887-015-0332-9
 received in 2014-04-25, accepted in 2015-02-06,  发布年份 2015
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【 摘 要 】

Background

Treating severe childhood obesity has proven difficult with inconsistent treatment results. This study reports the results of the implementation of a childhood obesity chronic care treatment protocol.

Methods

Patients aged 5 to 18 years with a body mass index (BMI) above the 99th percentile for sex and age were eligible for inclusion. At baseline patients’ height, weight, and tanner stages were measured, as well as parents’ socioeconomic status (SES) and family structure. Parental weight and height were self-reported. An individualised treatment plan including numerous advices was developed in collaboration with the patient and the family. Patients’ height and weight were measured at subsequent visits. There were no exclusion criteria.

Results

Three-hundred-thirteen (141 boys) were seen in the clinic in the period of February 2010 to March 2013. At inclusion, the median age of patients was 11.1 years and the median BMI standard deviation score (SDS) was 3.24 in boys and 2.85 in girls. After 1 year of treatment, the mean BMI SDS difference was −0.30 (95% CI: −0.39; −0.21, p < 0.0001) in boys and −0.19 (95% CI: −0.25; −0.13, p < 0.0001) in girls. After 2 years of treatment, the mean BMI SDS difference was −0.40 (95% CI: −0.56; −0.25, p < 0.0001) in boys and −0.24 (95% CI: −0.33; −0.15, p < 0.0001) in girls. During intervention 120 patients stopped treatment. Retention rates were 0.76 (95% CI: 0.71; 0.81) after one year and 0.57 (95% CI: 0.51; 0.63) after two years of treatment. Risk of dropout was independent of baseline characteristics. Median time spent by health care professionals was 4.5 hours per year per patient and the mean visit interval time was 2.7 months. The reductions in BMI SDS were dependent on gender, parental BMI, and family structure in girls, but independent of baseline BMI SDS, age, co-morbidity, SES, pubertal stage, place of referral, hours of treatment per year, and mean visit interval time.

Conclusions

The systematic use of the TCOCT protocol reduced the degree of childhood obesity with acceptable retention rates with a modest time-investment by health professionals.

【 授权许可】

   
2015 Most et al.; licensee BioMed Central.

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【 参考文献 】
  • [1]Wang Y, Lobstein T: Worldwide trends in childhood overweight and obesity. Int J Pediatr Obes 2006, 1(1):11-25.
  • [2]Han JC, Lawlor DA, Kimm SY: Childhood obesity. Lancet 2010, 375(9727):1737-48.
  • [3]Pearson S, Hansen B, Sorensen TI, Baker JL: Overweight and obesity trends in Copenhagen schoolchildren from 2002 to 2007. Acta Paediatr 2010, 99(11):1675-8.
  • [4]Keating CL, Moodie ML, Swinburn BA: The health-related quality of life of overweight and obese adolescents–a study measuring body mass index and adolescent-reported perceptions. Int J Pediatr Obes 2011, 6(5–6):434-41.
  • [5]Freedman DS, Khan LK, Serdula MK, Dietz WH, Srinivasan SR, Berenson GS: The relation of childhood BMI to adult adiposity: the Bogalusa heart study. Pediatrics 2005, 115(1):22-7.
  • [6]Park MH, Sovio U, Viner RM, Hardy RJ, Kinra S: Overweight in childhood, adolescence and adulthood and cardiovascular risk in later life: pooled analysis of three british birth cohorts. PLoS One 2013, 8(7):e70684.
  • [7]Weiss R, Dziura J, Burgert TS, Tamborlane WV, Taksali SE, Yeckel CW, et al.: Obesity and the metabolic syndrome in children and adolescents. N Engl J Med 2004, 350(23):2362-74.
  • [8]Renehan AG, Tyson M, Egger M, Heller RF, Zwahlen M: Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet 2008, 371(9612):569-78.
  • [9]Withrow D, Alter DA: The economic burden of obesity worldwide: a systematic review of the direct costs of obesity. Obes Rev 2011, 12(2):131-41.
  • [10]Recognition of Obesity as a Disease. http://www.npr.org/documents/2013/jun/ama-resolution-obesity.pdf
  • [11]Kalarchian MA, Levine MD, Arslanian SA, Ewing LJ, Houck PR, Cheng Y, et al.: Family-based treatment of severe pediatric obesity: randomized, controlled trial. Pediatrics 2009, 124(4):1060-8.
  • [12]Barlow SE: Expert Committee: Expert committee recommendations regarding the prevention, assessment, and treatment of child and adolescent overweight and obesity: summary report. Pediatrics 2007, 120(Suppl 4):S164-92.
  • [13]Waters E, de Silva-Sanigorski A, Hall BJ, Brown T, Campbell KJ, Gao Y, et al.: Interventions for preventing obesity in children. Cochrane Database Syst Rev 2011, 12:CD001871.
  • [14]Elfhag K, Rossner S: Who succeeds in maintaining weight loss? A conceptual review of factors associated with weight loss maintenance and weight regain. Obes Rev 2005, 6(1):67-85.
  • [15]Gunnarsdottir T, Njardvik U, Olafsdottir AS, Craighead LW, Bjarnason R: The role of parental motivation in family-based treatment for childhood obesity. Obesity (Silver Spring) 2011, 19(8):1654-62.
  • [16]Boutelle KN, Cafri G, Crow SJ: Parent predictors of child weight change in family based behavioral obesity treatment. Obesity (Silver Spring) 2012, 20(7):1539-43.
  • [17]Holm JC, Gamborg M, Bille DS, Gr Nb KHN, Ward LC, Faerk J: Chronic care treatment of obese children and adolescents. Int J Pediatr Obes 2011, 6(3–4):188-96.
  • [18]Krebs NF, Himes JH, Jacobson D, Nicklas TA, Guilday P, Styne D: Assessment of child and adolescent overweight and obesity. Pediatrics 2007, 120(Suppl 4):S193-228.
  • [19]Davis MM, Gance-Cleveland B, Hassink S, Johnson R, Paradis G, Resnicow K: Recommendations for prevention of childhood obesity. Pediatrics 2007, 120(Suppl 4):S229-53.
  • [20]Spear BA, Barlow SE, Ervin C, Ludwig DS, Saelens BE, Schetzina KE, et al.: Recommendations for treatment of child and adolescent overweight and obesity. Pediatrics 2007, 120(Suppl 4):S254-88.
  • [21]Collins CE, Warren J, Neve M, McCoy P, Stokes BJ: Measuring effectiveness of dietetic interventions in child obesity: a systematic review of randomized trials. Arch Pediatr Adolesc Med 2006, 160(9):906-22.
  • [22]Nysom K, Molgaard C, Hutchings B, Michaelsen KF: Body mass index of 0 to 45-y-old Danes: reference values and comparison with published European reference values. Int J Obes Relat Metab Disord 2001, 25(2):177-84.
  • [23]BC-418 Segmental Body Composition Analyzer http://www.tanita.com/en/bc-418/
  • [24]World Health Organization: Global database on Body Mass Index http://apps.who.int/bmi/index.jsp?introPage=intro_3.html
  • [25]Statistics Denmark: SOCIO - Danmarks Statistiks Socioøkonomiske Klassifikation 1997. 1st edition. Danmarks Statistik, Denmark; 1997.
  • [26]Videregivelse af patientjournaloplysninger http://sundhedsstyrelsen.dk/da/sundhed/behandling-og-rettigheder/patientjournaloplysninger
  • [27]Guidelines about Notification etc. of a Biomedical Research Project to the Committee System on Biomedical Research Ethics http://www.cvk.sum.dk/English/guidelinesaboutnotification.aspx
  • [28]Reilly JJ, Armstrong J, Dorosty AR, Emmett PM, Ness A, Rogers I, et al.: Early life risk factors for obesity in childhood: cohort study. BMJ 2005, 330(7504):1357.
  • [29]Reinehr T, Kleber M, Lass N, Toschke AM: Body mass index patterns over 5 y in obese children motivated to participate in a 1-y lifestyle intervention: age as a predictor of long-term success. Am J Clin Nutr 2010, 91(5):1165-71.
  • [30]Knop C, Singer V, Uysal Y, Schaefer A, Wolters B, Reinehr T: Extremely obese children respond better than extremely obese adolescents to lifestyle interventions. Pediatr Obes 2015, 10(1):7-14.
  • [31]Yannakoulia M, Papanikolaou K, Hatzopoulou I, Efstathiou E, Papoutsakis C, Dedoussis GV: Association between family divorce and children’s BMI and meal patterns: the GENDAI Study. Obesity (Silver Spring) 2008, 16(6):1382-7.
  • [32]Arkes J: Longitudinal association between marital disruption and child BMI and obesity. Obesity (Silver Spring) 2012, 20(8):1696-702.
  • [33]Monasta L, Batty GD, Macaluso A, Ronfani L, Lutje V, Bavcar A, et al.: Interventions for the prevention of overweight and obesity in preschool children: a systematic review of randomized controlled trials. Obes Rev 2011, 12(5):e107-18.
  • [34]Perri MG, Nezu AM, Patti ET, McCann KL: Effect of length of treatment on weight loss. J Consult Clin Psychol 1989, 57(3):450-2.
  • [35]Reinehr T, Widhalm K, l’Allemand D, Wiegand S, Wabitsch M, Holl RW, et al.: Two-year follow-up in 21,784 overweight children and adolescents with lifestyle intervention. Obesity (Silver Spring) 2009, 17(6):1196-9.
  • [36]de Niet J, Timman R, Jongejan M, Passchier J, van den Akker E: Predictors of participant dropout at various stages of a pediatric lifestyle program. Pediatrics 2011, 127(1):e164-70.
  • [37]Reinehr T, Kleber M, Toschke AM: Lifestyle intervention in obese children is associated with a decrease of the metabolic syndrome prevalence. Atherosclerosis 2009, 207(1):174-80.
  • [38]Reinehr T, Andler W: Changes in the atherogenic risk factor profile according to degree of weight loss. Arch Dis Child 2004, 89(5):419-22.
  • [39]Ho M, Garnett SP, Baur L, Burrows T, Stewart L, Neve M, et al.: Effectiveness of lifestyle interventions in child obesity: systematic review with meta-analysis. Pediatrics 2012, 130(6):e1647-71.
  • [40]Lass N, Kleber M, Winkel K, Wunsch R, Reinehr T: Effect of lifestyle intervention on features of polycystic ovarian syndrome, metabolic syndrome, and intima-media thickness in obese adolescent girls. J Clin Endocrinol Metab 2011, 96(11):3533-40.
  • [41]Reinehr T: Lifestyle intervention in childhood obesity: changes and challenges. Nat Rev Endocrinol 2013, 9(10):607-14.
  • [42]Nielsen TR, Gamborg M, Fonvig CE, Kloppenborg J, Hvidt KN, Ibsen H, et al.: Changes in lipidemia during chronic care treatment of childhood obesity. Child Obes 2012, 8(6):533-41.
  • [43]Hvidt KN, Olsen MH, Ibsen H, Holm JC: Effect of changes in BMI and waist circumference on ambulatory blood pressure in obese children and adolescents. J Hypertens 2014, 32(7):1470-7. discussion 1477
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