A home-based approach to managing multi-drug resistant tuberculosis in Uganda: a case report

AIDS Research and Therapy

Emmanuel Luyirika¹  Henry Nsobya¹  Richard Batamwita¹  Pheona Busingye¹  William Musoke¹  Lillian Nabiddo¹  Yvonne Karamagi¹  Barbara Mukasa¹ 

[1] Mildmay Centre, PO Box 24985, Kampala, Uganda

关键词: Sub-Saharan Africa;    East Africa;    Home-based care;    Home-care;    MDR-TB;    Multi-drug resistant;    Tuberculosis;    HIV;   

Others  :  789667
DOI  :  10.1186/1742-6405-9-12

 received in 2012-02-29, accepted in 2012-04-23,  发布年份 2012

【 摘 要 】

This case report describes an HIV-positive patient with recurrent tuberculosis in Uganda. After several failed courses of treatment, the patient was diagnosed with multi-drug resistant tuberculosis (MDR-TB). As adequate in-patient facilities were unavailable, we advised the patient to remain at home, and he received treatment at home via his family and a community nurse. The patient had a successful clearance of tuberculosis. This strategy of home-based care represents an important opportunity for treatment of patients in East Africa, where human resource constraints and inadequate hospital facilities exist for complex patients at high risk of infection to others.

【 授权许可】

   
2012 Luyirika et al; licensee BioMed Central Ltd.

【 参考文献 】

• [1]Gandhi NR, Moll AP, Lalloo U, Pawinski R, Zeller K, Moodley P, et al.: Successful integration of tuberculosis and HIV treatment in rural South Africa: the Sizonq'oba study. J Acquir Immune Devic Syndr 2009, 50:37-43.
• [2]Uganda Ministry of Health: The Republic of Uganda. National Tuberculosis and Leprosy Programme; Tuberculosis Case Management Desk Aide. Uganda. 2006.
• [3]Uganda Ministry of Health: National Antiretroviral Treatment And Care Guidelines for Adults and Children. Uganda. 2003.
• [4]World Health Organization: Antiretroviral Therapy for HIV infection in Adults and Adolescents: Recommendations for a Public Health Approach. Geneva. 2006.
• [5]Ford N: Pills not prison - drug resistant TB in South Africa. [http://www.essentialdrugs.org/edrug/archive/200702/msg00022.php;] webcite 2007.
• [6]Decroo T, Telfer B, Biot M, et al.: Distribution of antiretroviral treatment through self-forming groups of patients in Tete province, Mozambique. J Acquir Immune Devic Syndr 2011, 56:e39-e44.
• [7]Decroo T, Panunzi I, das Dores C, et al.: Lessons learned during down referral of antiretroviral treatment in Tete, Mozambique. J Int AIDS Soc 2009, 12:6. BioMed Central Full Text