Cell culture models: Time course of cellular accumulation of 99mTc-HMPAO

3rd Annual Applied Science and Engineering Conference

工业技术;自然科学

Sintya, E.^1

Faculty of Medicine and Health Sciences, Warmadewa University, Indonesia^1

关键词: Cell culture models;    Cell pellets;    Time course;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/434/1/012339/pdf
DOI  :  10.1088/1757-899X/434/1/012339

来源: IOP

【 摘 要 】

The accumulation of 99mTc-HMPAO was studied and compared at two different temperatures. This experiment shows besides temperature, time and efficiency of gama detector also give a significant affect to the result. Overall, the radioactivity rate is decrease as time goes in the supernatant samples, however the accumulation of 99mTc-HMPAO within the cells increases. In addition, in both the supernatant and the cell pellets, the values of the activity were lower at 4oC compared to 37oC showing they had a reduced ability to accumulate the 99mTc-HMPAO.