Thermal Stability and Surface Wettability Studies of Polylactic Acid/Halloysite Nanotube Nanocomposite Scaffold for Tissue Engineering Studies

Malaysian Technical Universities Conference on Engineering and Technology 2017

Mohd Nizar, M.^1 ; Hamzah, M.S.A.^2 ; Abd Razak, S.I.^2,3,4 ; Mat Nayan, N.H.^1,4

Faculty of Engineering Technology, Universiti Tun Hussein Onn Malaysia, Parit Raja, Johor Bahru

86400, Malaysia^1

Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, Skudai, Johor

81310, Malaysia^2

IJN-UTM Cardiovascular Engineering Centre, Universiti Teknologi Malaysia, Skudai, Johor

81310, Malaysia^3

Medical Devices and Technology Group, Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, Skudai, Johor

81310, Malaysia^4

关键词: Extraction method;    Halloysite nanotubes;    High potential;    Nanocomposite scaffolds;    Poly lactic acid;    Porous scaffold;    Positive impacts;    Surface wettability;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/318/1/012006/pdf
DOI  :  10.1088/1757-899X/318/1/012006

来源: IOP

【 摘 要 】

This paper reports the preliminary study about the incorporation of halloysite nanotubes (HNT) into polylactic acid (PLA) scaffold to improve the thermal resistance and surface wettability properties. The fabrication of the porous scaffold requires a simple yet effective technique with low-cost materials within freeze extraction method. The thermal stability of PLA/HNT scaffold compared to neat PLA scaffold achieved with increased content of HNT by 5 wt%. Moreover, the surface wettability of the scaffold also shows a positive impact with high content of HNT by 5 wt%. This new nanocomposite scaffold may have high potential as a suitable template for tissue regeneration.