Synthesis and Characterization of Hydroxyapatite-Collagen-Chitosan (HA/Col/Chi) Composite Coated on Ti6Al4V

International Conference on Chemistry and Material Science 2017

化学;材料科学

Charlena^1 ; Bikharudin, Ahmad^2 ; Wahyudi, Setyanto Tri^3

Department of Chemistry, Bogor Agricultural University, Bogor

16680, Indonesia^1

Department of Chemistry, Gadjah Mada University, Yogyakarta

55281, Indonesia^2

Department of Physic, Bogor Agricultural University, Bogor

16680, Indonesia^3

关键词: Corrosion resistance tests;    Cytocompatibility;    In-vitro;    Pulmonary artery endothelium;    Synthesis and characterizations;    Ti-6al-4v;    Ti-6Al-4V alloy;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/299/1/012028/pdf
DOI  :  10.1088/1757-899X/299/1/012028

学科分类：材料科学（综合）

来源: IOP

【 摘 要 】

HA-collagen-chitosan (HA/col/chi) composite is developed to increase bioactivity adhesiveness between the metal and the material composite and to improve corrosion resistance. The Ti6Al4V alloy was coated by soaking in HA/col/chi composite at room temperature and then allowed to stand for 5, 6, and 7 days. Diffraction pattern analysis of the coated Ti6Al4V alloy showed that the dominant phase were HA and Ti6Al4V alloy. Corrosion resistance test in media by using 0.9% NaCl showed the corrosion rate at the level of 0.3567 mpy, which was better than that of the uncoated Ti6Al4V alloy (0.4152 mpy). In vitro cytocompatibility assay on endothelial cell of calf pulmonary artery endothelium (CPAE) (ATCC-CCL 209) showed there was no toxicity in the cell culture with the percent inhibition of 33.33% after 72 hours of incubation.