Decreasing Free Radicals Level on High Risk Person After Vitamin C and E Supplement Treatment

1st Annual Applied Science and Engineering Conference

工业技术;自然科学

Sitorus, M.S.^1 ; Anggraini, D.R.^1 ; Hidayat^2

Anatomy Departement, Medical Faculty, University of Sumatera Utara, Indonesia^1

Biochemistry Departement, Medical Faculty, University of Sumatera Utara, Indonesia^2

关键词: Air pollutants;    Average ages;    Gasoline stations;    Global issues;    Malonaldehyde;    Motor vehicle emissions;    Non-enzymatic antioxidants;    Pollution level;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/180/1/012093/pdf
DOI  :  10.1088/1757-899X/180/1/012093

来源: IOP

【 摘 要 】

Has become a global issue that the increase in global warming mainly caused by high air pollution levels which are donated by motor vehicle emissions. As a rapidly developing country, Indonesia becomes vulnerable to health problems related to air pollution. Excessive free radicals that is produced by air pollution can initiate stress oxidative. Already known that, stress oxidative trigger many health problems. Vitamin C and E is a non enzymatic antioxidant that can neutralize free radicals. This study aims to investigate the decreasing free radicals level by administering vitamin C and E. This research using pre and post experimental design study. There are 24 operators gasoline station Pertamina as samples, with an average age of 26 years. The samples were divided into 4 groups. Group 1 (control), group 2, were given vitamin C doses of 500mg / day, group 3 was given vitamin E doses of 250 IU / day and the group 4 was given a combination of vitamins C and E. The treatment was given for 30 days. Free radicals level is obtained from malonaldehyde (MDA) level by spectrophotometer. Before treatment the average of MDA level is 5.540 μm. After the treatment, MDA is significantly decreased become 3.992 μm (T-test, sig