Development new radiopharmaceutical based on 5-thio-d- glucose labeled technetium-99m

8th International Scientific Conference "Issues of Physics and Technology in Science, Industry and Medicine"

物理学;工业技术;医药卫生

Stasyuk, E.S.^1 ; Skuridin, V.S.^1 ; Ilina, E.A.^1 ; Rogov, A.S.^1 ; Nesterov, E.A.^1 ; Sadkin, V.L.^1 ; Larionova, L.A.^1 ; Varlamova, N.V.^1 ; Zelchan, R.^2

National Research Tomsk Polytechnic University, Tomsk, Russia^1

Tomsk Cancer Research Institute, Tomsk, Russia^2

关键词: Biomedical testing;    International development;    Malignant tumors;    Technetium 99;    Technetium-99m;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/135/1/012044/pdf
DOI  :  10.1088/1757-899X/135/1/012044

来源: IOP

【 摘 要 】

The article considers the obtaining and possibility of using 5-thio-D-glucose labeled technetium-99m for the diagnosis of malignant tumors by single photon emission computed tomography. The analysis of the level of international developments of radiopharmaceuticals based on derivatives of glucose has been carried out. Also the article provides information on of using experimental batches of lyophilisate on the basis of 5-thio-D-glucose for preliminary biomedical testing on the mice.