5th International Symposium on Coherent Optical Radiation of Semiconductor Compounds and Structures | |
Radioprotective Action of Low-Intensity Light into the Red Absorption Band of Endogenous Molecular Oxygen | |
Ivanov, A.V.^1 ; Mashalov, A.A.^1 ; Zakharov, S.D.^2,3 | |
Blokhin Russian Cancer Research Center, Moscow | |
115478, Russia^1 | |
Division of Quantum Radiophysics, Lebedev Physical Institute, Russian Academy of Sciences, Moscow | |
119991, Russia^2 | |
National Research Nuclear University MEPhI, Moscow | |
115409, Russia^3 | |
关键词: Low-intensity; Malignant tumors; Optical technique; Oxygen effect; Radiation field; Radiation injury; Radioprotection; Radioprotectors; | |
Others : https://iopscience.iop.org/article/10.1088/1742-6596/740/1/012014/pdf DOI : 10.1088/1742-6596/740/1/012014 |
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来源: IOP | |
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【 摘 要 】
Application of ionizing radiation in oncology (radiation therapy) is a widespread way to eliminate malignant tumors. Normal tissues are inevitable included in any radiation field, and their reliable protection is actual till now. All attempts to solve the problem are based on search of effective radioprotectors, i.e. chemical compounds of various classes, which should be entered into the patient. To date about 50,000 compounds with some radioprotection properties had been tested, but the most effective of them have been simultaneously the most toxic. Here the preliminary results of researches devoted to development of an optical technique on basis of the light-oxygen effect for the protection of women with breast cancer from side effects of the radiation therapy are presented. A low intensity emission of the semiconductor laser in a red spectral interval was used to excite a very small quantity of endogenous molecular oxygen in O2(1Δg) state. It is shown, that application of the method at occurrence of earliest signs of radiation injury allows notably reducing dangerous breaks in radiation therapy course.
【 预 览 】
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Radioprotective Action of Low-Intensity Light into the Red Absorption Band of Endogenous Molecular Oxygen | 818KB | ![]() |