会议论文详细信息
5th International Symposium on Coherent Optical Radiation of Semiconductor Compounds and Structures
Radioprotective Action of Low-Intensity Light into the Red Absorption Band of Endogenous Molecular Oxygen
Ivanov, A.V.^1 ; Mashalov, A.A.^1 ; Zakharov, S.D.^2,3
Blokhin Russian Cancer Research Center, Moscow
115478, Russia^1
Division of Quantum Radiophysics, Lebedev Physical Institute, Russian Academy of Sciences, Moscow
119991, Russia^2
National Research Nuclear University MEPhI, Moscow
115409, Russia^3
关键词: Low-intensity;    Malignant tumors;    Optical technique;    Oxygen effect;    Radiation field;    Radiation injury;    Radioprotection;    Radioprotectors;   
Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/740/1/012014/pdf
DOI  :  10.1088/1742-6596/740/1/012014
来源: IOP
PDF
【 摘 要 】

Application of ionizing radiation in oncology (radiation therapy) is a widespread way to eliminate malignant tumors. Normal tissues are inevitable included in any radiation field, and their reliable protection is actual till now. All attempts to solve the problem are based on search of effective radioprotectors, i.e. chemical compounds of various classes, which should be entered into the patient. To date about 50,000 compounds with some radioprotection properties had been tested, but the most effective of them have been simultaneously the most toxic. Here the preliminary results of researches devoted to development of an optical technique on basis of the light-oxygen effect for the protection of women with breast cancer from side effects of the radiation therapy are presented. A low intensity emission of the semiconductor laser in a red spectral interval was used to excite a very small quantity of endogenous molecular oxygen in O2(1Δg) state. It is shown, that application of the method at occurrence of earliest signs of radiation injury allows notably reducing dangerous breaks in radiation therapy course.

【 预 览 】
附件列表
Files Size Format View
Radioprotective Action of Low-Intensity Light into the Red Absorption Band of Endogenous Molecular Oxygen 818KB PDF download
  文献评价指标  
  下载次数:14次 浏览次数:41次