Contributions of secondary fragmentation by carbon ion beams in water phantom: Monte Carlo simulation

10th International Seminar on Medical Physics; 1st AMDI International Oncology Symposium

物理学;医药卫生

Ying, C.K.^1 ; Bolst, David^2 ; Tran, Linh T.^2 ; Guatelli, Susanna^2 ; Rosenfeld, A.B.^2 ; Kamil, W.A.^3

Advanced Medical and Dental Institute, AMDI, Universiti Sains Malaysia, Bertam, Kepala Batas, Penang

13200, Malaysia^1

Centre of Medical Radiation Physics, University of Wollongong, NSW

2522, Australia^2

School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu

16150, Malaysia^3

关键词: Carbon ion beams;    Carbon ion therapy;    Dose distributions;    Heavy particles;    Light charged particles;    Mixed radiation fields;    Relative biological effectiveness;    Secondary fragmentation;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/851/1/012033/pdf
DOI  :  10.1088/1742-6596/851/1/012033

学科分类：卫生学

来源: IOP

【 摘 要 】

Heavy-particle therapy such as carbon ion therapy is currently very popular because of its superior conformality in terms of dose distribution and higher Relative Biological Effectiveness (RBE). However, carbon ion beams produce a complex mixed radiation field, which needs to be fully characterised. In this study, the fragmentation of a 290 MeV/u primary carbon ion beam was studied using the Geant4 Monte Carlo Toolkit. When the primary carbon ion beam interacts with water, secondary light charged particles (H, He, Li, Be, B) and fast neutrons are produced, contributing to the dose, especially after the distal edge of the Bragg peak.