Personalized radiosynoviorthese: dosimetry treatment planning

1st International Symposium 'Physics, Engineering and Technologies for Bio-Medicine'

医药卫生;物理学;工业技术

Trukhin, A.A.^1,2 ; Nikitaev, V.G.^1 ; Yu Dubov, L.^1 ; Shtotsky, Yu.V.^1

National Research Nuclear University, MEPhI, Russia^1

Endocrinology Research Centre, Russia^2

关键词: Empirical approach;    Support method;    Synovium;    Therapeutic activity;    Treatment planning;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/784/1/012007/pdf
DOI  :  10.1088/1742-6596/784/1/012007

来源: IOP

【 摘 要 】

This work is devoted to the quantitative dosimetric support method for endoradyotherapy of inflammatory joints diseases. To reduce inflammation in synovium radiopharmaceutical is injected intraarticularly and provides local ablation of excessive synovial tissue. Present-day guidelines give empirical approaches to therapeutic activity selection. Such approaches lead to 20% untreated patients. Article shows way to improvement of cure level by introduction of dosimetric support.