Facility for thermoradiotherapy of deep-seated tumors

2nd Conference on Plasma & Laser Research and Technologies

Fadeev, A.M.^1 ; Ivanov, S.M.^1,2 ; Perelstein, E.A.^3 ; Polozov, S.M.^1

National Research Nuclear University, Moscow Engineering Physics Institute, Moscow

115409, Russia^1

N.N. Blokhin Russian Cancer Research Center, Moscow

114478, Russia^2

Joint Institute for Nuclear Research, Dubna

141980, Russia^3

关键词: Cancer research;    Deep-seated tumors;    Experimental prototype;    Linear electron accelerator;    Local heating;    Survival rate;    Thermoradiotherapy;    Treatment methods;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/747/1/012076/pdf
DOI  :  10.1088/1742-6596/747/1/012076

来源: IOP

【 摘 要 】

Therapeutic hyperthermia in combination with radiotherapy which is realized by means of modern linear electron accelerators (called thermoradiotherapy) is one of widely used contemporary cancer treatment methods. Hyperthermia provides increasing of the tumors sensibility to radiation. Thus the radiation dose could be decreased. The experience achieved at N.N. Blokhin Russian Cancer Research Center during 40 years shows that 5-year survival rate increases (15-40%) for a number of cancer types and localization. High dose can be easily delivered to the deep seated tumors but local heating is a big problem so far. One possible way to solve the problem of deep tissues local heating is discussed in this article, the brief review of previous simulations and latest results for experimental prototype setup are presented.