Blood glucose regulation in diabetics. A flatness based nonlinear control simulation study

20th Argentinean Bioengineering Society Congress

物理学;生物科学

Cocha, Guillermo^1 ; Podestá, Melina^2 ; Mazzadi, Alejandro^3 ; Amorena, Carlos^3 ; D'Atellis, Carlos^4

Departamento de Ingenieria Eléctrica, Universidad Tecnológica Nacional Facultad, Regional La Plata, Argentina^1

Insute de Ingenieria y Agronomia, Universdad Nacional Arturo Jauretche, Av. Calchaqui 6300, Florencio Varela, Argentina^2

CESIMA UNSAM, Buenos Aires Argentina, Argentina^3

Grupo de Ing. Clinica U.T.N.

Dto. de Matemática, Univ. Favaloro

Centro de Matemática Aplicada, UNSAM, Buenos Aires Argentina, Argentina^4

关键词: Blood glucose regulations;    Flat systems;    Flatness-based control;    Human system;    Minimal model;    Non linear control;    System variables;    Time derivative;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/705/1/012027/pdf
DOI  :  10.1088/1742-6596/705/1/012027

学科分类：生物科学（综合）

来源: IOP

【 摘 要 】

Flat systems are a generalization of linear systems, but the techniques used for controlling flat systems are much different than many of the existing techniques for linear systems. In this paper we present the flatness-based control of blood glucose regulation in human system. A non-near model, he Bergman Minimal Model, is used o represent he dynamics of blood regulation in humans and because of the flatness property, he system variables can be expressed as functions of he at output and heir time derivatives and a control aw developed.