Contrast medium usage reduction in abdominal computed tomography by using high-iodinated concentration contrast medium

13th South-East Asian Congress of Medical Physics 2015

物理学;医药卫生

Suwannasri, A.^1,2 ; Kaewlai, R.^2 ; Asavaphatiboon, S.^2

School of Medical Physics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand^1

Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand^2

关键词: Confidence interval;    Contrast Enhancement;    Intravenous contrast;    Iodinated contrast medium;    Qualitative images;    Quantitative and qualitative analysis;    Significance levels;    Statistically significant difference;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/694/1/012045/pdf
DOI  :  10.1088/1742-6596/694/1/012045

学科分类：卫生学

来源: IOP

【 摘 要 】

This study was to determine if administration of a low volume high-concentration iodinated contrast medium can preserve image quality in comparison with regular-concentration intravenous contrast medium in patient undergoing contrast-enhancement abdominal computed tomography (CT). Eighty-four patients were randomly divided into 3 groups of similar iodine delivery rate; A: 1.2 cc/kg of iomeprol-400, B: 1.0 cc/kg of iomeprol-400 and C: 1.5 cc/kg of ioversol-350. Contrast enhancement of the liver parenchyma, pancreas and aorta was quantitatively measured in Hounsfield units and qualitative assessed by a radiologist. T-test was used to evaluate contrast enhancement, and Chi-square test was used to evaluate qualitative image assessment, at significance level of 0.05 with 95% confidence intervals. There were no statistically significant differences in contrast enhancement of liver parenchyma and pancreas between group A and group C in both quantitative and qualitative analyses. Group C showed superior vascular enhancement to group A and B on quantitative analysis.