Fluorocarbon compounds in MRI diagnostics and medical therapy

2nd International Conference and Young Scientist School "Magnetic resonance imaging in biomedical research"

Pirogov, Yu^1

Department of Physics, Lomonosov Moscow State University, Moscow, Russia^1

关键词: Cardioprotective effect;    Chemical formulae;    Larmor frequencies;    Living organisms;    Medical therapy;    MRI contrasts;    Oxygen delivery;    Substitute products;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/677/1/012004/pdf
DOI  :  10.1088/1742-6596/677/1/012004

来源: IOP

【 摘 要 】

The lecture describes the application of fluorocarbon compounds as blood substitutes and contrasting preparations in MRI diagnostics. A blood substitute product fluorocarbon Perfluorane® has shown effectiveness in oxygen delivery to the tissues of living organisms, and cardioprotective effect which does not depend on the patient's blood group. Inclusion of paramagnetic atoms (gadolinium, iron, etc.) to the Perfluorane® chemical formula creates a new compound with high MRI contrast efficiencies at Larmor frequencies of protons so and fluorine-19 nuclei.