Cleavage enhancement of specific chemical bonds in DNA-Cisplatin complexes induced by X-rays

28th International Conference on Photonic, Electronic and Atomic Collisions

Zheng, Yi^1 ; Yao, Xiaobin^1 ; Luo, Xinglan^1 ; Fu, Xianzhi^1

Fujian Provincial Key Laboratory of Photocatalysis, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou

350002, China^1

关键词: Bond cleavages;    Cis-platin;    DNA complex;    X ray irradiation;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/488/14/142010/pdf
DOI  :  10.1088/1742-6596/488/14/142010

来源: IOP

【 摘 要 】

The chemical bond transformation of cisplatin-DNA complexes can be probed efficiently by XPS which provides a concomitant X-ray irradiation source as well. The presence to Pt could considerably increase formation of the SE induced by X-ray and that the further interaction of these LEE with DNA leads to the enhancement of bond cleavages.