Delta-Notch Lateral Inhibition within the Organ of Corti

2013 Joint IMEKO (International Measurement Confederation) TC1-TC7-TC13 Symposium: Measurement Across Physical and Behavioural Sciences

Summers, R.^1 ; Abdulla, T.^1 ; Luff, R.^1

SEESE, Loughborough University, Ashby Road, Loughborough, LE11 3TU, United Kingdom^1

关键词: Brain functions;    Emergent property;    Human Connectome;    Lateral inhibition;    Model representation;    Organ of corti;    Signalling network;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/459/1/012013/pdf
DOI  :  10.1088/1742-6596/459/1/012013

来源: IOP

【 摘 要 】

Lateral inhibition is described as an emergent property of the Delta-Notch signalling network. Two separate model representations of lateral inhibition are proposed for different purposes. One provides information about bioenergetics while the other has the capability to produce a physical representation. It is proposed that both can be used in further studies of the sensory pathways in the human connectome model of brain function.