Kitchen Waste as a Novel Available Substrate for Prodigiosin Production by Serratia Marcescense

2018 5th International Conference on Coastal and Ocean Engineering

Xia, Shunxiang^1,2 ; Veony, Enjelia^2 ; Yang, Qiyin^1

College of Life Science, Nanjing Normal University, Nanjing

210046, China^1

Department of Petroleum Engineering, University of Houston, Houston

TX

77023, United States^2

关键词: Agitation speed;    Anti-tumor activities;    Incubation time;    Inoculum level;    Liquid volume;    Nitrogen sources;    Serratia marcescens;    Substrate concentrations;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/171/1/012037/pdf
DOI  :  10.1088/1755-1315/171/1/012037

来源: IOP

【 摘 要 】

As a compound with antitumor activities, prodigiosin was produced by Serratia marcescens with kitchen waste as a substrate. The initial yield of prodigiosin was 223mg/l and can be further improved with supplementation of nitrogen source and inductor to the medium. A 290% increase of the prodigiosin production was achieved with 1% peptone and 0.2% proline. Physiological fermentation factors such as incubation time (36h), substrate concentration (35g/l), pH of the medium (pH 8.0), and fermentation parameter such as temperature (28?), agitation speed (150rpm), inoculum level (1%), and liquid volume (20/150ml) all have impact on the prodigiosin production. With optimization, the maximum prodigiosin yield was 890mg/l and kitchen waste was proved to be a novel and economic substrate for prodigison production.