Identification of Active Compounds in the Root of Merung (Coptosapelta tomentosa Valeton K. Heyne)

1st International Conference on Tropical Studies and Its Application

Fitriyana^1

Chemical Engineering Department, State Polytechnic of Samarinda, Jl. Dr. Cipto Mangunkusumo Kampus, Gunung Lipan-Samarinda

75131, Indonesia^1

关键词: 2-furancarboxaldehyde;    Active compounds;    Decanoic acid;    Ethyl acetates;    Gas chromatography-mass spectrometries (GC-MS);    GC-MS analysis;    Literature studies;    Medical treatment;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/144/1/012020/pdf
DOI  :  10.1088/1755-1315/144/1/012020

来源: IOP

【 摘 要 】

The roots of Merung (Coptosapelta tomentosa Valeton K. Heyne) are a group of shrubs usually found on the margins of secondary dryland forest. Empirically, local people have been using the roots of Merung for medical treatment. However, some researches show that the plant extract is used as a poisonous material applied on the tip of the arrow (dart). Based on the online literature study, there are less than 5 articles that provide information about the active compound of this root extract. This study aimed to give additional information more deeply about the content of active compound of Merung root extract in three fractions, n-hexane (nonpolar), ethyl acetate (semi polar) and methanol (polar). The extract was then analysed using Gas Chromatography-Mass Spectrometry (GC-MS). GC-MS analysis of root extract in n-hexane showed there were 56 compounds, with the main compound being decanoic acid, methyl ester (peak 5, 10.13%), 11-Octadecenoic acid, methyl ester (peak 15, 10.43%) and 1H-Pyrazole, 3- (4-chlorophenyl) -4, 5-dihydro-1-phenyl (peak 43, 11.25%). Extracts in ethyl acetate fraction obtained 81 compounds. The largest component is Benzoic acid (peak 19, 22.40%), whereas in methanol there are 38 compounds, of which the main component is 2-Furancarboxaldehyde, 5-(hydroxyl methyl) (peak 29, 30.46%).