Isolation and Identification of Active Compounds from Papaya Plants and Activities as Antimicrobial

12th Joint Conference on Chemistry

Prasetya, A.T.^1 ; Mursiti, S.^2 ; Maryan, S.^2 ; Jati, N.K.^2

Doctoral Degree of Postgraduate, Semarang State University, Kampus Kelud-Petompon-Gajah Mungkur, Semarang

50237, Indonesia^1

Chemistry Department, Faculty of Mathematics and Natural Science, Semarang State University, Sekaran Gunungpati Semarang

50229, Indonesia^2

关键词: Active compounds;    Anti-bacterial activity;    Anti-fungal activity;    Diethyl ethers;    Diethyl-ether solvent;    Ethyl acetates;    Gram-negative bacteria;    Isolation and identification;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/349/1/012007/pdf
DOI  :  10.1088/1757-899X/349/1/012007

来源: IOP

【 摘 要 】

Extraction and isolation of papaya seeds and leaves (Carica papaya L) has been performed using n-hexane and ethanol solvents. Further isolation of the extract obtained using ethyl acetate and diethyl ether solvents. The result of the phytochemical test of papaya extract obtained by mixture of an active compound of flavonoids, alkaloids, tannins, steroids, and saponins. Ethyl acetate isolates containing only flavonoids and diethyl ether isolates contain only alkaloids. Extracts and isolates from papaya plants had gram-positive antibacterial activity greater than the gram-negative bacteria, but both did not have antifungal activity. Papaya extracts have greater antibacterial activity than flavonoid isolates and alkaloid isolates. Strong antibacterial inhibitory sequences are extracts of papaya plants, flavonoid isolates, and alkaloid isolates.