Association of serum uric acid level and blood pressure in type 2 diabetes mellitus

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Savira, M.^1 ; Rusdiana^2 ; Syahputra, M.^2

Department of Physiology, Faculty of Medical, University of Sumatera Utara, Jl. dr. Mansur Kampus USU, Medan

20155, Indonesia^1

Department of Biochemistry, Faculty of Medical, University of Sumatera Utara, Jl. dr. Mansur Kampus USU, Medan

20155, Indonesia^2

关键词: Alcohol intake;    Cardio-vascular disease;    Cross-sectional design;    Diabetes mellitus;    Elevated level;    Metabolic syndromes;    Renal functions;    Type 2 diabetes mellitus;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012169/pdf
DOI  :  10.1088/1755-1315/125/1/012169

来源: IOP

【 摘 要 】

Uric acid is an end product of purine degradation in humans and primarily excreted through urine. In adulthood, concentrations rise steadily over time and vary with height, body weight, blood pressure, renal function, and alcohol intake. Uric acid is known as anti-oxidant, it has a beneficial role in diseases. Elevated serum uric acid associated with anincreased risk of cardiovascular disease. It has been found that elevated levels of uric acid associated with high risks of acomplication of type 2 diabetes mellitus and It has astrong association between elevated uric acid levels and obesity, metabolic syndrome, diabetes mellitus, hypertension, cardiovascular and renal disorders. The aim of the study analyzed the association between serum uric acid level and blood pressure in type 2 diabetes mellitus patients. This research is descriptive analytic research with a cross sectional design included 50 diabetic subjects aged over 40 years old. Subjects picked by consecutive sampling then we examined the weight, height, waist size, blood pressure, fasting blood sugar, and serum uric acid level. Statistical analysis using chi-square found that there was no significant association between serum uric acid level and systole and diastole pressure in type 2 diabetes mellitus patients (p>0.005).