Comparison of microbial pattern in early and late onset neonatal sepsis in referral center Haji Adam Malik hospital Medan Indonesia

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Hasibuan, B.S.^1,2

Department of Child Health, Faculty of Medicine, Universitas Sumatera Utara, Jl. Dr. Mansyur No. 5, Medan

20155, Indonesia^1

H. Adam Malik General Hospital, Medan, Indonesia^2

关键词: Antibiotic resistance;    Blood culture;    Causative agents;    Change time;    Descriptive studies;    Incidence rate;    Klebsiella pneumonia;    Perinatology;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012053/pdf
DOI  :  10.1088/1755-1315/125/1/012053

来源: IOP

【 摘 要 】

Neonatal sepsis contributes a significant rate of infants mortality and morbidity. The pathogens are diverse from region to another and change time to time even in the same place. To analyze the microbial pattern in early and late onset neonatal sepsis andthe pattern of antibiotic resistance of the causative microbes at one of referral center hospital in Indonesia, Haji Adam Malik Hospital, a cross-sectional descriptive study was conducted on neonates with sepsis diagnosis proven with positive blood culture within one year period (2015-2016). Among 626 neonates admitted to perinatology unit, the total of 154 neonates was proven to have neonatal sepsis with positive blood culture with the incidence rate 24.6%. Seventy-nine (51.3%) neonates were diagnosed with early onset sepsis while 75 (48,7%) neonates had late-onset sepsis. Klebsiella pneumonia was the most commonly isolated organism in both early and late onset sepsis, encompassing 19.5% of cases. Periodic surveillance of the causative agents of neonatal sepsis is needed to implement the rational, empirical choice of antibiotic prescription while waiting for blood culture result to come out.