Production of Nanopropolis Using High Pressure Ball Mill Homogenizer

12th Congress of Indonesian Soc. for Biochemistry and Molecular Biology in Conjunction With The 2nd Int. Conf. "Collaboration Seminar of Chemistry and Industry

生物科学;化学

Hamdi, D.^1 ; Wijanarko, A.^1 ; Hermansyah, H.^1 ; Asih, S.C.^1 ; Sahlan, M.^1^2

Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok

16425, Indonesia^1

Research Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Depok

16425, Indonesia^2

关键词: Anti-bacterial activity;    Bacillus Subtilis;    Bioactive compounds;    Casein micelles;    Drug delivery system;    nanopropolis;    Particle size analyzers;    Staphylococcus aureus;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/217/1/012014/pdf
DOI  :  10.1088/1755-1315/217/1/012014

学科分类：生物科学（综合）

来源: IOP

【 摘 要 】

Propolis is one of the product that produces by bees. Propolis commonly used as a supplement because it has a bioactive compound. Propolis is hydrophobic, so it is not absorbed by the body very well, that's why it needs other technologies to solve this problem. Encapsulation is one of the answers because this technology has "drug delivery systems." The purpose of this study is to look at the efficiency of coating, particle size of nanopropolis and antibacterial activity. The result of this research shows that the efficiency of propolis coatings by flavonoids is 94,71%. Particle Size Analyzer (PSA) is used to measure the particle size. The result is nanopropolis has an average diameter 75,7 nm and 83,9 nm. The antibacterial activity of propolis against Escherichia coli, Bacillus subtilis, and Staphylococcus aureus was detected but not in nanopropolis.