Influence of Calcium-Phosphate Coating on Wettability of Hybrid Piezoelectric Scaffolds

16th International Conference of Students and Young Scientists "Prospects of Fundamental Sciences Development"

自然科学（总论）

Zviagin, A.^1 ; Chernozem, R.^1 ; Surmeneva, M.^1 ; Loza, K.^2 ; Prymak, O.^2 ; Ulbricht, M.^3 ; Epple, M.^2 ; Surmenev, R.^1

Physical Materials Science and Composite Materials Centre, National Research Tomsk Polytechnic University, Tomsk

634050, Russia^1

Inorganic Chemistry and Center for Nanointegration Duisburg-Essen (CeNIDE), University of Duisburg-Essen, Essen

45141, Germany^2

Technical Chemistry II, University of Duisburg-Essen, Essen

45141, Germany^3

关键词: Biodegradable scaffold;    Deposition cycles;    Ethanol concentrations;    Hydrophobic surfaces;    Poly(3-hydroxybutyrate);    Polyanilines (PAni);    Surface wetting;    Water contact angle (WCA);   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/597/1/012061/pdf
DOI  :  10.1088/1757-899X/597/1/012061

学科分类：自然科学（综合）

来源: IOP

【 摘 要 】

Herein, electrospun biodegradable scaffolds based on polycaprolactone (PCL), poly(3-hydroxybutyrate) (PHB) and polyaniline (PANi) polymers were fabricated. A calcium-phosphate (CaP) coating was deposited on the surface of the scaffolds via an improved soaking process. Influence of the deposition cycles and ethanol concentration in the solution on the relative increase of the scaffolds weight and water contact angle (WCA) are determined. The characterization of the molecular and crystal structure confirmed the formation of CaP phase. Importantly, WCA results showed that the pristine scaffolds have the hydrophobic surface, while the deposition of CaP coating onto scaffolds allows to significantly improve the surface wetting behavior, and infiltration of the water droplets into the CaP-coated scaffolds was observed. Thus, the fabricated hybrid biodegradable piezoelectric scaffolds can be utilized for regenerative medicine.