Effect of the inflammatory conditions and albumin presence on the corrosion behavior of grade 5 Titanium alloy in saliva biological solution

International Conference on Innovative Research - ICIR EUROINVENT 2019

Dragus, L.^1^2 ; Benea, L.^1 ; Simionescu, N.^1 ; Ravoiu, A.^1^2 ; Neaga, V.^1

Competences Center: Interfaces-Tribocorrosion-Electrochemical Systems (CC-ITES), Faculty of Engineering, Dunarea de Jos University of Galati, 47 Domneasca street, Galati, Romania^1

Faculty of Medicine and Pharmacy, Dunarea de Jos University of Galati, 35 Alexandru Ioan Cuza Street, Galati

800010, Romania^2

关键词: Biological environments;    Biological solutions;    ELectrochemical methods;    Inflammatory conditions;    Materials engineering;    Metallic biomaterials;    Multi-disciplinary approach;    Reactive oxygen species;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/572/1/012005/pdf
DOI  :  10.1088/1757-899X/572/1/012005

来源: IOP

【 摘 要 】

The field of biomaterials imposes a multidisciplinary approach that requires the involvement of sciences such as biology, medicine, chemistry and materials engineering so that the material implanted in a living organism does not cause any adverse reaction. This research area of biomaterials is considered as fascinating and challenging. It's fascinating because of its potential applications and the need to improve the quality of life. It is challenging due to the various complexities it faces when biomaterials encounter biological environments for the longevity of life by maintaining or restoring tissue or organ functions. Metallic biomaterials are used as pivots for anchoring dental implants and as parts of orthodontic devices such as crowns and bridges of prostheses. Ti-6Al-4V is well known as a corrosion resistant alloy for dentistry applications due to this film of titanium oxide formed on its surface. However, the inflammatory conditions ad protein presence could affect the corrosion resistance of this alloy. Our research work aims to investigate the effect of albumin and inflammatory conditions to corrosion resistance of Ti-6Al-4V in saliva Fusayama Meyer biological solution. In order to simulate the peri-implant inflammatory conditions in vitro studies were conducted with addition of hydrogen peroxide (reactive oxygen species, found during inflammation) and albumin the most typical protein of biological fluids. Electrochemical methods were applied for corrosion investigations. The results provide evidence that titanium's alloy corrosion resistance is affected by inflammatory conditions and albumin presence in saliva biological solution.