Synthesis, Characterization and Insilco Study of New 1,3-Oxazolone-5-(4-Cl)-one and - Oxazolone-5-(4-NO2)-one Derivatives

2nd International Scientific Conference (Pure Sciences, Brilliant Creativity and Renewed Building)

Al-Hazam, Hanan A.^1 ; Mahood, Abdulbari M.^2

Deparment of Chemistry, College of Science, Basrah University, Iraq^1

Department of Pharmaceutical Chemistry, College of Pharmacy, University of Kerbala, Iraq^2

关键词: 1H NMR spectroscopy;    Insilco;    Sebacoyl chloride;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/571/1/012083/pdf
DOI  :  10.1088/1757-899X/571/1/012083

来源: IOP

【 摘 要 】

In this study two new compounds are prepared 1,3-Oxazolone-5-(4-Cl)-one and Oxazolone-5-(4-NO2)-one derivatives by a reaction of glycine with sebacoyl chloride. The two compoundswere identified and characterized by CHN, IR and 1H-NMR Spectroscopy. Both derivativesshow different biological activity according to the program.