NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS,,362012年
Blanchard, D. Caroline, Defensor, Erwin B., Meyza, Ksenia Z., Pobbe, Roger L. H., Pearson, Brandon L., Bolivar, Valerie J., Blanchard, Robert J.
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] NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS,,472014年
Occelli, Valeria, Spence, Charles, Zampini, Massimiliano
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NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS,,372013年
Li, Yan-Chun, Gao, Wen-Jun
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NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS,,962019年
Valero-Cabre, Antoni, Amengual, Julia L., Stengel, Chloe, Pascual-Leone, Alvaro, Coubard, Olivier A.
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5 Understanding taurine CNS activity using alternative zebrafish models (vol 83, pg 525, 2018) [期刊论文]
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS,,902018年
Mezzomo, Nathana J., Fontana, Barbara D., Kalueff, Allan V., Barcellos, Leonardo J. G., Rosemberg, Denis B.
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Taurine is a highly abundant amino acid in the brain. Although the potential neuroactive role of taurine in vertebrates has long been recognized, the underlying molecular mechanisms related to its pleiotropic effects in the brain remain poorly understood. Due to the genetic tractability, rich behavioral repertoire, neurochemical conservation, and small size, the zebrafish (Danio rerio) has emerged as a powerful candidate for neuropsychopharmacology investigation and in vivo drug screening. Here, we summarize the main physiological roles of taurine in mammals, including neuromodulation, osmoregulation, membrane stabilization, and antioxidant action. In this context, we also highlight how zebrafish models of brain disorders may present interesting approaches to assess molecular mechanisms underlying positive effects of taurine in the brain. Finally, we outline recent advances in zebrafish drug screening that significantly improve neuropsychiatric translational research and small molecule screens.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS,,372013年
Owen, Dawn, Andrews, Marcus H., Matthews, Stephen G.
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