Association between CASP7 and CASP14 genetic polymorphisms and the risk of childhood leukemia

Childhood leukemia;Genetic variation;Apoptosis;CASP7;CASP14

의과대학 의과학과 ;

University:서울대학교 대학원

关键词: Childhood leukemia;    Genetic variation;    Apoptosis;    CASP7;    CASP14;   

Others  :  http://s-space.snu.ac.kr/bitstream/10371/132963/1/000000004329.pdf

美国|英语

来源: Seoul National University Open Repository

【 摘 要 】

OR=0.34, 95% CI 0.18-0.63, respectively). When stratified by subtype groups (ALL and AML), CASP14 was still statistically significant in each subtype. This study suggests that genetic polymorphisms in apoptosis and cell cycle related genes might play a role in childhood leukemia development.