Prognostic Value of the Nodal Ratio and Ki-67 Expression in Breast Cancer Patients Treated with Postmastectomy Radiotherapy

Breast neoplasms;Ki-67 antigen;Lymph nodes;Mastectomy;Radiotherapy;610

의과대학 임상의과학과 ;

University:서울대학교 대학원

关键词: Breast neoplasms;    Ki-67 antigen;    Lymph nodes;    Mastectomy;    Radiotherapy;    610;   

Others  :  http://s-space.snu.ac.kr/bitstream/10371/132407/1/000000017354.pdf

美国|英语

来源: Seoul National University Open Repository

【 摘 要 】

n=30). DFS and OS had no association with intrinsic subtypes (p = 0.249 and p = 0.202, respectively). When our prognostic model was applied to luminal A subtype, there was a marginal association in DFS (p = 0.078), while not in OS (p = 0.173).Conclusions: For breast can¬cer patients undergoing postmastectomy radiotherapy, nodal ratio and Ki-67 are potential prog¬nostic factors. A model using these factors might help predict a poor prognosis. Whether nodal ratio and Ki-67 are also prognostic for different setting of systemic therapy, preoperative or postopera¬tive, warrants further study to develop a more sophisticated prognostic model.